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New coronavirus strain in the UK: Scientists’ concerns and what we know so far

The rise in new COVID strain, a mutation in the novel coronavirus, has raised concerns whether COVID-19 vaccines currently under development, will now work against the variant.

December 21, 2020 / 15:57 IST

A new variant of the novel coronavirus has been identified in the United Kingdom. England’s Chief Medical Officer Chris Whitty said on December 19 that the new variant of the coronavirus, which causes COVID-19, can spread faster.

Scientists are working to confirm if the mutation leads to a higher mortality rate or cause more severe illnesses.

Also Read: India suspends all flights from UK till Dec 31

Whitty said that the virus mutation was likely to be the reason behind the sudden rise in COVID-19 cases around the capital and southeast of the country. “As a result of the rapid spread of the new variant, preliminary modelling data and rapidly rising incidence rates in the South East, the New and Emerging Respiratory Virus Threats Advisory Group (NERVTAG) now consider that the new strain can spread more quickly,” Whitty added.

The emergence of the new strain of the deadly virus has forced the UK government to put London and southern England under an emergency lockdown ahead of Christmas. The UK had reported over 20.4 lakh COVID-19 cases as of December 21, including more than 67,400 deaths.

COVID-19 Vaccine

Frequently Asked Questions

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How does a vaccine work?

A vaccine works by mimicking a natural infection. A vaccine not only induces immune response to protect people from any future COVID-19 infection, but also helps quickly build herd immunity to put an end to the pandemic. Herd immunity occurs when a sufficient percentage of a population becomes immune to a disease, making the spread of disease from person to person unlikely. The good news is that SARS-CoV-2 virus has been fairly stable, which increases the viability of a vaccine.

How many types of vaccines are there?

There are broadly four types of vaccine — one, a vaccine based on the whole virus (this could be either inactivated, or an attenuated [weakened] virus vaccine); two, a non-replicating viral vector vaccine that uses a benign virus as vector that carries the antigen of SARS-CoV; three, nucleic-acid vaccines that have genetic material like DNA and RNA of antigens like spike protein given to a person, helping human cells decode genetic material and produce the vaccine; and four, protein subunit vaccine wherein the recombinant proteins of SARS-COV-2 along with an adjuvant (booster) is given as a vaccine.

What does it take to develop a vaccine of this kind?

Vaccine development is a long, complex process. Unlike drugs that are given to people with a diseased, vaccines are given to healthy people and also vulnerable sections such as children, pregnant women and the elderly. So rigorous tests are compulsory. History says that the fastest time it took to develop a vaccine is five years, but it usually takes double or sometimes triple that time.

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France, Germany, Italy, Belgium, Austria and the Netherlands, among others, have temporarily banned flights from the UK due to the spread of a new strain. India’s Union Health Ministry also called an urgent meeting on December 21 to discuss the development.

What we know so far

All viruses have the ability to mutate. Thus, the emergence of this novel coronavirus variant was not unexpected. It is to be noted that this is not the first time the SARS-Cov-2 has mutated. Scientists had identified nearly 200 genetic mutations in the virus as early as May. Only some of these mutations are significant.

The Guardian quoted Whitty as saying that the new strain could be up to 70 percent more transmissible and could increase the R value by 0.4 or more. So far, it has not appeared to raise the risk of severe illness or the mortality rate.

Follow our LIVE blog for latest updates on new coronavirus strain

What we don’t not know yet

Scientists are concerned about the new variant’s spike protein. The spike protein is the part of the virus that allows it to infiltrate cells in the lungs, throat, etc. This happens because due to the spike protein’s interaction with the ACE-2 receptor. The mutation on the spike protein may make it easier for the virus to interact with ACE-2.

The mutations has also raised concerns whether vaccines currently under development will work against the variant. Vaccines are designed to develop antibodies against the spike protein. Thus, there is a possibility that the mutation may not allow the vaccine to develop antibodies. Scientists would be monitoring this to take appropriate actions.

COVID-19 Vaccine Tracker: What you need to know about manufacturing and pricing

Are existing protocols sufficient to stop its transmission?

Scientists currently do not have enough information about the new variant to know if it will impact existing guidelines such as social distancing and mask wearing.

As the virus is believed to be more transmissible, it would lead to many more deaths even with the same mortality rate. Thus, safety protocols will remain in place.

Click here for Moneycontrol’s full coverage of the coronavirus pandemic

Moneycontrol News
first published: Dec 21, 2020 09:15 am

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