HomeNewscoronavirusCOVID-19 update | Chile becomes Latin America's coronavirus vaccination champion

COVID-19 update | Chile becomes Latin America's coronavirus vaccination champion

With more than 25% of its people having received at least one shot, the country of 19 million on South America's Pacific coast is the champion of Latin America, and globally it is just behind Israel, the United Arab Emirates and the United Kingdom.

March 14, 2021 / 19:21 IST
Source: Reuters

Chile After being among the world's hardest-hit nations with COVID-19, Chile is now near the top among countries at vaccinating its population against the virus.

With more than 25% of its people having received at least one shot, the country of 19 million on South America's Pacific coast is the champion of Latin America, and globally it is just behind Israel, the United Arab Emirates and the United Kingdom.

That's a far cry from the beginning of the pandemic, when Chile was criticized over its inability to trace and isolate infected people.

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So what is the secret to its success?

COVID-19 Vaccine

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A vaccine works by mimicking a natural infection. A vaccine not only induces immune response to protect people from any future COVID-19 infection, but also helps quickly build herd immunity to put an end to the pandemic. Herd immunity occurs when a sufficient percentage of a population becomes immune to a disease, making the spread of disease from person to person unlikely. The good news is that SARS-CoV-2 virus has been fairly stable, which increases the viability of a vaccine.

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There are broadly four types of vaccine — one, a vaccine based on the whole virus (this could be either inactivated, or an attenuated [weakened] virus vaccine); two, a non-replicating viral vector vaccine that uses a benign virus as vector that carries the antigen of SARS-CoV; three, nucleic-acid vaccines that have genetic material like DNA and RNA of antigens like spike protein given to a person, helping human cells decode genetic material and produce the vaccine; and four, protein subunit vaccine wherein the recombinant proteins of SARS-COV-2 along with an adjuvant (booster) is given as a vaccine.

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Government officials and health experts say it was the country's early negotiations with vaccine producers, as well as its past experience with robust vaccination programs, a record praised by the World Health Organization.

During the first months of the pandemic, the headlines in Chile were bleak, with the country's intensive care units almost full and the government unable to control the viruss spread despite restrictions that included mandatory lockdowns.

But another story was developing in parallel that few people knew about, one that had begun months before and would later guarantee Chile fast access to vaccines.

Andrs Couve, Chiles minister of science, told The Associated Press that formal negotiations with vaccine-producing companies started last April, only a month after COVID-19 was declared a pandemic.

By May, Couve said, a team of experts and officials presented a plan to President Sebastin Piera, including a road map about how to use the country's network of trade agreements and its previous contacts with pharmaceutical companies to get vaccines once they were developed. Recommendations included being part of clinical trials.

This effort was helped by contacts made months earlier in China. In October 2019, Chilean biochemist Dr. Alexis Kalergis had traveled to Beijing with two Chilean colleagues for an international congress on immunology. There Kalergis met experts from the Chinese pharmaceutical Sinovac Biotech Ltd.

Kalergis had already approached Sinovac about working on vaccine research. So when China announced in January 2020 that it had identified a new virus, and within weeks the world saw it spreading around the globe, Kalergis knew he needed to reach out to his colleagues at Sinovac.

Taking advantage of our experience, the contacts and the interest that we expressed we started conversations with Sinovac, said Kalergis, director of the Milenio Institute for Immunology and Immunotherapy at Chiles Catholic University.

He spoke to Sinovac colleagues in January and February 2020, then went to Catholic University Dean Ignacio Snchez with the details, saying they needed to be passed on to the government.

Snchez approached Chile's health minister and foreign secretary, urging early negotiations with Sinovac and other pharmaceuticals and for Chile to be part of their clinical trials. The ministers agreed, and the Chilean government began making diplomatic contacts.

By June, long before any other country in Latin America, Chile had secured a contract with Sinovac, which agreed to deliver an early batch once the vaccine was authorized, Kalergis said.

Rodrigo Yez, undersecretary for international economic relations and lead negotiator with companies to get the vaccines, said Chile understood from the beginning that it needed to work with different pharmaceutical companies at the same time.

We looked at different alternatives and didnt put all the eggs in the same basket, he said.

Chile was part of a Sinovac clinical trial that started in December and involved 2,300 medical workers. The government has not published its results, saying only that they were good.

Trials for vaccines by AstraZeneca, Janssen and the Chinese pharmaceutical CanSino were also done in Chile, and those results also have not been disclosed.

Chile received its first vaccine doses in December, some 21,000 from Pfizer, but they were fewer than promised. The country immediately began vaccinating medical workers. By the end of January, Chile received the first 4 million doses from Sinovac and was able to speed up inoculation. Massive vaccination started in February.

Chile was administering more than 100,000 shots almost daily since early February, and that more than tripled this week.

On Wednesday, it reached a daily global record of 1.3 shots per 100 inhabitants, followed by Israel with 1.04 doses, according to Our World in Data, a collaboration between researchers at the University of Oxford and the nonprofit Global Change Data Lab.

No other country in Latin America has had anything near Chile's success. Brazil, for example, has vaccinated only 4% of its population, and Argentina around 3%.

Health Minister Enrique Pars said Chile has now secured 35 million doses to vaccinate 15 million people, and its already helping other countries. Earlier this month, Chilean authorities donated 20,000 Sinovac doses to Paraguay and the same amount to Ecuador.

Chile had good planning and wisely used the resources it has to make bilateral agreements with some producers, Jarbas Barbosa, deputy director of the Pan American Health Organization, said this week.

This is not the first time Chile has conducted a successful vaccination program. Last year, between March and April when the virus was emerging, Chilean authorities vaccinated 8 million people against the flu.

Mario Patio, 75, was among the first to be vaccinated with a Sinovac dose in February at a school in Lo Prado, a poor residential area of Santiago.

Everything was perfect, fast, with an excellent service, well organized," said Patio, who was getting his second shot on Saturday. For me, the vaccine means to be calmer."

Associated Press
first published: Mar 14, 2021 07:21 pm

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