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Study shows regular exercise not just builds muscles, but also boosts immunity

New research suggests that regular, long-term endurance exercise can slow down immune ageing. In older adults, it boosts natural killer cells, reduces inflammation, and keeps the body better prepared for illness or stress. Scientists believe exercise doesn't just train your muscles, it also helps train your immune system.

October 28, 2025 / 14:25 IST
As per a study, regular exercise strengthens immunity by a great degree (Picture Credit: Unsplash)

Exercise might be doing more for you than toned muscles and a strong heart. A recent research shows that long-term endurance training, think running, swimming or cycling, may also slow down how quickly your immune system ages. Scientists have discovered that older adults who’ve kept active for decades show fewer signs of cellular fatigue and inflammation, and more resilience to stress. It seems that exercise, literally, keeps your immune system fighting fit.

For years, we’ve known that physical activity is vital for heart health and mental wellbeing. Now, thanks to a joint study involving Brazilian and German researchers, we’ve got solid proof that it’s also a crucial part of immune health. “It’s as if exercise also trains the immune system,” says Luciele Minuzzi, researcher at Justus Liebig University in Germany. The findings show that older people with a history of endurance exercise have immune cells that behave more like those of much younger adults.

Exercise supports immunity: The team focused on natural killer (NK) cells—white blood cells that seek and destroy viruses, abnormal cells and even early-stage cancer. In older adults who had trained for decades, these NK cells were more adaptable, burned energy more efficiently and resisted exhaustion, even under stress.

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Immune system stays young, lowers long-term inflammation: Regular exercisers had fewer inflammatory markers and more anti-inflammatory ones, showing that lifelong movement helps control chronic inflammation, often a root cause of ageing and illness.

Boosts immune efficiency under stress: Even when NK cells from fit older adults were exposed to strong stressors like adrenaline blockers or rapamycin (a drug that disrupts cell growth), they held up. Those from sedentary individuals did not.

Trains your immune response: Master athletes (people training for over 20 years) had a more regulated inflammatory response than younger athletes after an exercise session. “Their bodies know how to handle inflammatory episodes without overreacting,” says Minuzzi.

Improves energy metabolism in cells: The NK cells from trained individuals were metabolically more efficient. In plain terms, they had the energy to keep working longer and didn’t tire out as quickly when fighting off stressors.

Supports healthy ageing: By avoiding the exaggerated immune responses linked to chronic disease, exercise-trained immune systems may pave the way for ageing with fewer health issues.
“This type of training adapts the immune system over time, making it more balanced and prepared,” says Minuzzi. After all, our immune systems don’t just need protection, they need practice. And exercise might just be the best rehearsal.

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FAQs on benefits of regular exercise:

1. Why is regular exercise important?
It strengthens your heart, muscles, and bones while improving overall energy and mood.

2. How does exercise help mental health?
It reduces stress, anxiety, and depression by releasing “feel-good” hormones like endorphins.

3. Can exercise help with weight control?
Yes. Regular physical activity burns calories and boosts metabolism, helping maintain a healthy weight.

4. How often should I exercise?
Aim for at least 150 minutes of moderate or 75 minutes of vigorous activity per week.

5. What are long-term benefits of regular exercise?It lowers the risk of heart disease, diabetes, and certain cancers — and helps you live longer.

Disclaimer: This article, including health and fitness advice, only provides generic information. Don’t treat it as a substitute for qualified medical opinion. Always consult a specialist for a specific health diagnosis

Namita S Kalla is a senior journalist who writes about different aspects of modern life that include lifestyle, health, fashion, beauty, and entertainment.
first published: Oct 28, 2025 02:25 pm

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