Mounjaro becomes India’s no. 2 pharma brand: Everything you need to know about the fat-loss drug

From diabetes management to fat-loss fame — Mounjaro has become India’s No. 2 pharma brand. Here’s what you need to know before trying it

Mounjaro (tirzepatide), the diabetes drug that turned into weight-loss sensation, has become the no. 2 pharma brand in India, according to the latest sales data. The drug’s rapid rise mirrors the nation's growing wave of weight-loss medication demand, fuelled by social media buzz, celebrity endorsements, and a cultural shift towards fat-loss solutions.

Mounjaro has now entered mainstream conversation, with online communities swapping experiences, dosage tips, and even before-and-after pictures. The result seen is a massive spike in demand that has pushed it to the top tier of India’s pharmaceutical market in record time.

What Is Mounjaro?

It was originally developed by Eli Lilly to treat type 2 diabetes, and is a part of a new class of injectable drugs called GLP-1 receptor agonists and GIP receptor agonists. These compounds mimic gut hormones that help regulate blood sugar, fullness and appetite.

The drug works in two primary ways:

It regulates blood glucose levels by improving insulin sensitivity and reducing the liver’s glucose output.

It also suppresses appetite and slows digestion, which will reduce calorie intake and helps in steady weight loss over time.

Also Read: India’s anti-obesity drug market grows fivefold in five years, led by GLP-1 therapies

In clinical trials, patients taking tirzepatide lost up to 20 per cent of their body weight — a result that rivals or even surpasses older GLP-1 drugs like Ozempic (semaglutide) and Wegovy, both made by Novo Nordisk.

What’s Driving the Boom?

The anti-obesity market in India has exploded over the past year due to various factors such as:

• The rise in metabolic and lifestyle diseases like diabetes, hypertension, and fatty liver, which often accompany obesity.
• There is growth in disposable income among urban consumers who are increasingly willing to pay for pharmaceutical shortcuts.
• Social media influence has glamourised rapid transformations, with viral hashtags like #OzempicFace and #MounjaroJourney have gone viral

Pharmacies and online health platforms are reporting record sales of prescriptions, with some doctors saying they have seen a boom in patients coming to them asking for Mounjaro by name — a rare phenomenon in India’s prescription-driven market.

Also Read: Weight loss drug Ozempic launch in India: Is it safe for diabetes patients? Does it control blood sugar?

How Drug Works in Your Body

Mounjaro belongs to a new class of dual acting incretin drugs. By stimulating both the GLP-1 and GIP receptors, Mounjaro promotes the postprandial augmentation of insulin secretion and the enhancement of glucose disposal. Simultaneously, Mounjaro helps the brain regulate appetite, forcing the user to drink less and eat less. It helps control the user’s appetite.

According to users, the improved weight loss and metabolic changes are the result of the dual mechanism of action. Other GLP-1 medications lack this functionality and are less effective.

Some side effects of Mounjaro may be unwanted. Nausea, vomiting, a feeling of fullness or constipation and fatigue are all potential side effects, especially in the first few weeks.

But these effects can involve side effects including nausea, constipation, vomiting and fatigue — especially in the early weeks of use.

Is It Safe and Effective?

Experts agree that Mounjaro is effective when used correctly, but not without risks. The drug may bring on gastrointestinal upset, gallbladder issues or, rarely, pancreatitis. It’s also contraindicated for individuals with certain thyroid disorders or a family history of medullary thyroid carcinoma.

There’s also concern about rebound weight gain once the medication is stopped.

Research indicates that a large number of users gain the weight back if they remain in their old ways or forget to taper off the injections gradually.

Also Read: Is Ozempic beneficial for you? Nutritionist explains how it can diminish your natural glow

The rise of Mounjaro signifies a turning point in India's views on wellness and weight. It shows how medical intervention is becoming more widely accepted for lifestyle problems that were previously thought to be behavioural or personal issues.

Experts argue that how society chooses to use drugs like Mounjaro is a more important question than whether they are effective.