Diet guide: More potassium in daily diet reduces Alzheimer’s risk, supports better brain health

Potassium and heart health: High blood pressure is a known risk factor for Alzheimer’s. Potassium’s ability to counterbalance sodium could provide added protection for the brain (Image: Canva)

People with early signs of cognitive decline often find themselves forgetting names, losing their way on familiar routes, or repeating stories within minutes. These small lapses are usually brushed off, but they could be early indicators of Alzheimer’s disease. Research, however, suggests that increasing potassium intake could offer a surprising defence against such cognitive issues and help delay the onset of Alzheimer’s.

Potassium and brain health:

A preclinical study using a transgenic mouse model of Alzheimer’s disease (APPswe/PS-1) discovered that increasing potassium intake in the early stages of the condition led to significant improvements in memory, learning, and brain health. Potassium-rich diet appeared to reduce the buildup of harmful brain proteins and inflammation, two major contributors to Alzheimer’s progression. Though conducted on mice, this study adds to a growing body of evidence suggesting that diet can play a crucial role in brain health.

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Here’s are 10 ways how potassium may help protect against Alzheimer’s:

• Lowers toxic proteins: Potassium intake reduced levels of amyloid-beta (Aβ1-42), a protein known to form plaques in the brain that disrupt cognitive function.

• Reduces tau damage: The diet helped decrease the presence of hyperphosphorylated tau proteins, which interfere with neuron communication.

• Supports brain plasticity: Potassium promoted recovery in long-term potentiation (LTP), a brain function critical for learning and memory.

• Improves memory: Mice given a potassium-rich diet performed better in memory and recognition tests, suggesting a positive impact on cognitive function.

• Reduces inflammation: The study showed a reduction in inflammatory markers, such as IL-6, and less activation of glial cells, both associated with brain degeneration.

• Protects against oxidative stress: Potassium helped reduce 4-HNE, a marker of oxidative stress that damages brain cells and accelerates Alzheimer’s.

• Alters plaque structure: While smaller plaques slightly increased, the more damaging, larger plaques became less prominent, suggesting potassium may alter their formation.

• Improves attention and focus: Potassium improved performance in tasks related to spatial and recognition memory, indicating better hippocampal function.

• Helps regulate blood pressure: Since high blood pressure is a known risk factor for Alzheimer’s, potassium’s ability to counterbalance sodium could provide added protection for the brain.

• Offers non-drug support: Most significantly, the study suggests that a potassium-enriched diet could be a low-risk, non-pharmacological approach to delay or reduce the onset of Alzheimer’s when introduced early.