China's Sinovac starts late stage trials for its COVID-19 vaccine

Sinovac said the study, which will be done in partnership with Brazilian vaccine producer the Instituto Butantan, would recruit nearly 9,000 healthcare professionals working in COVID-19 specialised facilities and start this month.

Reuters

July 07, 2020 / 11:29 IST

3 | NHS England in talks on rollout of potential COVID vaccine from December, says report: The National Health Service (NHS) is in talks with the British Medical Association (BMA) and others around mobilising the rollout of a potential COVID-19 vaccine from December, Pulse website for health professionals reported. >There is optimism around the first cohorts being given a vaccine in December but there is a 50/50 chance of the vaccine being available by that time, Pulse reported, citing a person close to the discussions.

China's Sinovac Biotech is starting Phase III trials of its potential coronavirus vaccine in Brazil, it said on Monday, becoming one of three companies to move into the late stages in the race to develop an inoculation against the disease.

It follows a fast-track approval for the trials by Brazilian regulators last week.

Sinovac said the study, which will be done in partnership with Brazilian vaccine producer the Instituto Butantan, would recruit nearly 9,000 healthcare professionals working in COVID-19 specialised facilities and start this month.

AstraZeneca's experimental COVID-19 vaccine, developed by researchers at the University of Oxford, and China National Pharmaceutical Group (Sinopharm) are the only other candidates in late-stage Phase III trials.

Moderna also plans to start its late-stage trial this month.

COVID-19 Vaccine

Frequently Asked Questions

How does a vaccine work?

A vaccine works by mimicking a natural infection. A vaccine not only induces immune response to protect people from any future COVID-19 infection, but also helps quickly build herd immunity to put an end to the pandemic. Herd immunity occurs when a sufficient percentage of a population becomes immune to a disease, making the spread of disease from person to person unlikely. The good news is that SARS-CoV-2 virus has been fairly stable, which increases the viability of a vaccine.

How many types of vaccines are there?

There are broadly four types of vaccine — one, a vaccine based on the whole virus (this could be either inactivated, or an attenuated [weakened] virus vaccine); two, a non-replicating viral vector vaccine that uses a benign virus as vector that carries the antigen of SARS-CoV; three, nucleic-acid vaccines that have genetic material like DNA and RNA of antigens like spike protein given to a person, helping human cells decode genetic material and produce the vaccine; and four, protein subunit vaccine wherein the recombinant proteins of SARS-COV-2 along with an adjuvant (booster) is given as a vaccine.

What does it take to develop a vaccine of this kind?

Vaccine development is a long, complex process. Unlike drugs that are given to people with a diseased, vaccines are given to healthy people and also vulnerable sections such as children, pregnant women and the elderly. So rigorous tests are compulsory. History says that the fastest time it took to develop a vaccine is five years, but it usually takes double or sometimes triple that time.

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