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HomeNewsIndiaCOVID-19 treatment: Centre to boost availability of Amphotericin B to fight mucormycosis aka black fungus

COVID-19 treatment: Centre to boost availability of Amphotericin B to fight mucormycosis aka black fungus

The COVID-19 survivors in India are facing another major health concern as mucormycosis -- also called the black fungus

May 12, 2021 / 13:46 IST
Pharma (Representational image: Shutterstock)

Pharma (Representational image: Shutterstock)

The government has taken steps to ramp up production of Amphotericin B, a medicine used to treat Mucormycosis, a fungal infection that is being reported in COVID-19 patients.

"The Government of India is therefore engaging with the manufacturers to ramp up production of the drug. The supply position is expected to improve with extra imports of this drug and increase in its production domestically," the Ministry of Chemicals and Fertilizers said in a statement.

The supply arrangements of the drug by National Pharmaceuticals Pricing Authority (NPPA).

"After reviewing the stock position with the manufacturers/importers, and the demand pattern of Amphotericin B the Department of Pharma, has on 11th May, 2021 , allocated this drug amongst the States/UTs based on expected supply that will be available from May 10 to May 31, 2021. States have been requested to put in place a mechanism for equitable distribution of supplies amongst Government and Private hospitals and health care agencies," the ministry said.

The COVID-19 survivors in India are facing another major health concern as mucormycosis -- also called the black fungus -- are on the rise among recovering and recovered patients, causing blindness or other serious issues.

COVID-19 Vaccine

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How does a vaccine work?

A vaccine works by mimicking a natural infection. A vaccine not only induces immune response to protect people from any future COVID-19 infection, but also helps quickly build herd immunity to put an end to the pandemic. Herd immunity occurs when a sufficient percentage of a population becomes immune to a disease, making the spread of disease from person to person unlikely. The good news is that SARS-CoV-2 virus has been fairly stable, which increases the viability of a vaccine.

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There are broadly four types of vaccine — one, a vaccine based on the whole virus (this could be either inactivated, or an attenuated [weakened] virus vaccine); two, a non-replicating viral vector vaccine that uses a benign virus as vector that carries the antigen of SARS-CoV; three, nucleic-acid vaccines that have genetic material like DNA and RNA of antigens like spike protein given to a person, helping human cells decode genetic material and produce the vaccine; and four, protein subunit vaccine wherein the recombinant proteins of SARS-COV-2 along with an adjuvant (booster) is given as a vaccine.

What does it take to develop a vaccine of this kind?

Vaccine development is a long, complex process. Unlike drugs that are given to people with a diseased, vaccines are given to healthy people and also vulnerable sections such as children, pregnant women and the elderly. So rigorous tests are compulsory. History says that the fastest time it took to develop a vaccine is five years, but it usually takes double or sometimes triple that time.

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Mucormycosis fungal infections maiming COVID-19 survivors in India: All you need to know about this 'black fungus'

Gujarat has so far reported over 100 cases of mucormycosis, which is a serious but rare fungal infection.

In Maharashtra, the worst coronavirus-affected state, at least eight COVID-19 survivors have lost vision in an eye due to mucormycosis and 200 others are being treated, said Dr Tatyarao Lahane, who heads the state government's Directorate of Medical Education and Research.

Follow our full coverage on COVID-19 here.

Moneycontrol News
first published: May 12, 2021 12:37 pm

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