Ozempic: A miracle weight-loss drug or dangerous trend? We examine

Understanding the efficacy of Ozempic. (Image: Freepik)

A once-obscure diabetes medication—Ozempic, also known as Semaglutide—has exploded in popularity, with social media and celebrity endorsements fueling a frenzy over its weight loss effects. Originally designed to regulate blood sugar in people with type 2 diabetes, Ozempic has become a household name among those seeking quick weight loss.

Amid rumours of Selena Gomez using Ozempic after she looked visibly thinner at the SAG awards, we reached out to experts to understand whether it is a safe and sustainable solution, or just another fleeting trend with hidden risks.

What is Ozempic?

Ozempic is a GLP-1 receptor agonist—a class of drugs that mimics the hormone glucagon-like peptide-1 (GLP-1). This hormone helps regulate blood sugar by increasing insulin release, slowing digestion and reducing appetite.

"Ozempic works by controlling hunger and increasing satiety, making people eat less," explains Dr Tushar Tayal, consultant, internal medicine at CK Birla Hospital, Gurugram.

While Ozempic is FDA-approved for type 2 diabetes, its weight loss effects have led to it widespread off-label use. A higher-dose version—Wegovy—has been specifically approved for obesity management.

How effective is Ozempic for weight loss?

Dr Vyankatesh Shivane, consultant diabetology and metabolic physician, Jaslok Hospital & Research Centre, Mumbai, says, "With Ozempic, we see dramatic weight loss—up to 15 to 20 percent in some cases. This not only helps with diabetes control but also lowers cardiovascular risk and improves metabolic health." Clinical trials suggest that higher doses of semaglutide (Wegovy) may lead to even greater weight reduction.

However, experts caution that weight loss results are highly dependent on continue use of the drug. "Once ap a patient stops taking Ozempic, weight regain is common if lifestyle changes are not maintained," Dr Shivane warns.

Also Read | Does Ozempic help in weight loss? Control blood sugar level, reduce hunger to stick to your fitness goals

The cons

While the weight loss benefits of Ozempic are impressive, the drug should not be used indiscriminately. There are side effects, and it is not suitable for everyone.

"Potential risks and side effects include gastrointestinal issues such as nausea, vomiting, diarrhea, and constipation. Rare but serious cases of pancreatic inflammation have been reported. Increased risk of gallstones due to rapid weight loss, possible thyroid cancer risk, and muscle loss have also been seen," Dr Tayal says. "People with type 1 diabetes and pregnant or breastfeeding women should avoid using Ozempic," he adds.

Also Read | Ozempic obsession: Hollywood’s weight loss fixation; why it is in spotlight once again

The growing popularity of Ozempic

Ozempic is being touted for its weight loss benefits. (Image: Freepik)

While Ozempic is not a replacement for insulin, Ozempic has gained notoriety, which can largely be attributed to social media and celebrity endorsements. Reports suggest that high-profile figures—including Hollywood celebrities and tech executives—have used it to achieve rapid weight loss.

"Social media has made Ozempic seem like a magic weight-loss solution. But without medical supervision, its misuse can be dangerous," Dr Prashant Patil, consultant pediatric endocrinologist at Narayana Health SRCC Children's Hospital, Mumbai advises.

The off-label use of Ozempic for weight loss has also raised ethical concerns. "There is a fine line between medical necessity and misuse. The increasing demand for Ozempic among non-diabetic individuals is concerning as it creates shortages for those who genuinely need it," Dr Jagadish Hiremath, public health expert, Bengaluru, points out.

Final verdict

Ozempic is undoubtedly a breakthrough in diabetes and obesity management, but it is not a miracle drug. Its use should be carefully monitored by a healthcare professional.

"Consult a doctor first. It works best when combined with a balanced diet and regular exercise, rather than as a shortcut," Dr Tayal concludes.

Disclaimer: This article, including health and fitness advice, only provides generic information. Don’t treat it as a substitute for qualified medical opinion. Always consult a specialist for specific health diagnosis.