HomeNewsWorldNext pandemic could be more lethal than COVID-19: Vaccine creator

Next pandemic could be more lethal than COVID-19: Vaccine creator

The novel coronavirus has killed 5.26 million people across the world, according to Johns Hopkins University, wiped out trillions of dollars in economic output and turned life upside down for billions of people.

December 06, 2021 / 14:17 IST
India has now reported 21 cases of the Omicron variant, 17 of which were reported on the same day of December 5. [Representative image]

Future pandemics could be even more lethal than COVID-19 so the lessons learned from the outbreak must not be squandered and the world should ensure it is prepared for the next viral onslaught, one of the creators of the Oxford-AstraZeneca vaccine said.

The novel coronavirus has killed 5.26 million people across the world, according to Johns Hopkins University, wiped out trillions of dollars in economic output and turned life upside down for billions of people.

"The truth is, the next one could be worse. It could be more contagious, or more lethal, or both," Sarah Gilbert said in the Richard Dimbleby Lecture, the BBC reported. "This will not be the last time a virus threatens our lives and our livelihoods."

Gilbert, a professor of vaccinology at the University of Oxford, said the world should make sure it is better prepared for the next virus.

"The advances we have made, and the knowledge we have gained, must not be lost," she said.

COVID-19 Vaccine

Frequently Asked Questions

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How does a vaccine work?

A vaccine works by mimicking a natural infection. A vaccine not only induces immune response to protect people from any future COVID-19 infection, but also helps quickly build herd immunity to put an end to the pandemic. Herd immunity occurs when a sufficient percentage of a population becomes immune to a disease, making the spread of disease from person to person unlikely. The good news is that SARS-CoV-2 virus has been fairly stable, which increases the viability of a vaccine.

How many types of vaccines are there?

There are broadly four types of vaccine — one, a vaccine based on the whole virus (this could be either inactivated, or an attenuated [weakened] virus vaccine); two, a non-replicating viral vector vaccine that uses a benign virus as vector that carries the antigen of SARS-CoV; three, nucleic-acid vaccines that have genetic material like DNA and RNA of antigens like spike protein given to a person, helping human cells decode genetic material and produce the vaccine; and four, protein subunit vaccine wherein the recombinant proteins of SARS-COV-2 along with an adjuvant (booster) is given as a vaccine.

What does it take to develop a vaccine of this kind?

Vaccine development is a long, complex process. Unlike drugs that are given to people with a diseased, vaccines are given to healthy people and also vulnerable sections such as children, pregnant women and the elderly. So rigorous tests are compulsory. History says that the fastest time it took to develop a vaccine is five years, but it usually takes double or sometimes triple that time.

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Efforts to end the COVID-19 pandemic have been uneven and fragmented, marked by limited access to vaccines in low-income countries while the "healthy and wealthy" in rich countries get boosters, health experts say.

A panel of health experts set up by the World Health Organisation to review the handling of the SARS-CoV-2 pandemic has called for permanent funding and for greater ability to investigate pandemics through a new treaty.

One proposal was for new financing of at least $10 billion a year for pandemic preparedness.

The COVID-19 outbreak was first detected in China in late 2019. Vaccines were developed against the virus in record time.

Gilbert said the Omicron variant’s spike protein contained mutations known to increase the transmissibility of the virus.

"There are additional changes that may mean antibodies induced by the vaccines, or by infection with other variants, may be less effective at preventing infection with Omicron," Gilbert said.

"Until we know more, we should be cautious, and take steps to slow down the spread of this new variant."

Reuters
first published: Dec 6, 2021 02:17 pm

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