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HomeNewsTrendsHealthWhat is a COVID-19 antibody test and how to get it done? All your questions answered

What is a COVID-19 antibody test and how to get it done? All your questions answered

Read on to know what are antibody tests according to ICMR and how do they help

July 11, 2020 / 14:29 IST
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Representative Image

With coronavirus cases touching 8 lakh in India, the government has decided to expand its testing capacity rapidly. As more people head to get tested COVID-19, one of the most common tests given to detect COVID-19 is the antibody test.

While antibody tests can't actively diagnose coronavirus infections it can check for proteins in the immune system, known as antibodies, through a blood sample. Their presence means a person was exposed to the virus and developed antibodies against it, which may mean that person has developed some immunity.

So what are the routine antibody tests available, and what is the difference between them?

Here's all you need to know:

Real-Time/RT-PCR- This test can take up to 90 samples at one time and can deliver results accurately. It takes up to 4-5 hours from receiving the sample to delivering the results, according to the recent guidelines the Indian Council for Medical Research (ICMR). It also mentions that this test is to be used to determine the likelihood of developing SARS-COV-2, a strain similar to COVID-19 whenever available.

COVID-19 Vaccine

Frequently Asked Questions

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How does a vaccine work?

A vaccine works by mimicking a natural infection. A vaccine not only induces immune response to protect people from any future COVID-19 infection, but also helps quickly build herd immunity to put an end to the pandemic. Herd immunity occurs when a sufficient percentage of a population becomes immune to a disease, making the spread of disease from person to person unlikely. The good news is that SARS-CoV-2 virus has been fairly stable, which increases the viability of a vaccine.

How many types of vaccines are there?

There are broadly four types of vaccine — one, a vaccine based on the whole virus (this could be either inactivated, or an attenuated [weakened] virus vaccine); two, a non-replicating viral vector vaccine that uses a benign virus as vector that carries the antigen of SARS-CoV; three, nucleic-acid vaccines that have genetic material like DNA and RNA of antigens like spike protein given to a person, helping human cells decode genetic material and produce the vaccine; and four, protein subunit vaccine wherein the recombinant proteins of SARS-COV-2 along with an adjuvant (booster) is given as a vaccine.

What does it take to develop a vaccine of this kind?

Vaccine development is a long, complex process. Unlike drugs that are given to people with a diseased, vaccines are given to healthy people and also vulnerable sections such as children, pregnant women and the elderly. So rigorous tests are compulsory. History says that the fastest time it took to develop a vaccine is five years, but it usually takes double or sometimes triple that time.

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The same report mentions guidelines for The TrueNat and CBNAAT sets, which can be used in the diagnosis of COVID-19 since there is the availability of customisable cartridges. In comparison to the Real-Time/RT PCR, this test has quicker turnaround time lasting about 30-60 minutes between receiving the sample and delivering the results but can administer only up to 1-4 samples in one run- limiting the number of people who can be tested in a day to 24-48 samples.

All COVID-19 tests conducted through these tests are fed directly into the ICMR data entry portal which helps them in getting national estimates on numbers of tests conducted.

ICMR has approved a total of 1,000 COVID-19 testing labs in both public (730) and private sector (270).

This includes RT-PCR labs (557); TrueNat Labs (363) and CBNAAT Labs (80), the guidelines said, adding that access to testing still remains largely a concern in a country like India, according to the report.

You can follow this link and search to find out COVID-19 testing labs in India.

Disclaimer:  This article is intended for educational purposes only. Please consult a physician or doctor before you take any of the diagnostic tests.

Moneycontrol News
first published: Jul 11, 2020 02:29 pm

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