Dr Reddy’s Laboratories and Global Response Aid (GRA) on January 27 announced the termination of Avigan (favipiravir) clinical trial conducted in Kuwait on moderate to severe COVID-19 patients in a hospital setting, as the data failed to show a statistically significant difference for the primary endpoint.
The data from the Kuwait study involving moderate-severe COVID-19 hospitalised patients did not show a statistically significant difference for the primary endpoint or the time taken to resolve hypoxia. However, low-risk category COVID-19 patients on the broad spectrum antiviral got discharged three days ahead of the placebo group.
GRA is an alliance focused on improving medical supply chain worldwide. Hypoxia is a condition in which the body is deprived of adequate oxygen supply. Hypoxia is the major symptom in patients with moderate-severe COVID-19.
While it took seven days or a day less than placebo for resolution of hypoxia in the Avigan arm.