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Cardiologist explains how high blood pressure fuels coronary heart disease

Hypertension (HTN) is a major risk factor for the development of coronary heart disease (CHD). Although there are many people who do not consider the risks posed by high blood pressure, its long-term impact on both the arteries as well as the heart is severe. Understanding this connection is critical for prevention, early diagnosis and improved heart health

September 26, 2025 / 10:45 IST
Hypertension may be symptomless, but its long-term effects on the heart and arteries make it one of the most dangerous risk factors for coronary heart disease. (Image: Pexels)

High blood pressure, or hypertension, is among the most significant contributors to cardiovascular disease worldwide. Frequently symptomless, this disease slowly affects the arteries, requiring the heart to work increasingly harder to do its job of pumping blood. Cumulatively, this strain causes the formation of coronary heart disease (CHD), a state when blood can no longer efficiently flow through the heart because plaque has built up over time.

High blood pressure speeds up the development of hardening and narrowing of the arteries. This decreases the amount of oxygen available to the heart muscle, bringing a person closer to experiencing chest pain or having a heart attack or developing heart failure. The longer hypertension is left uncontrolled the higher the risk of disastrous consequences, it highlights prevention and timely intervention.

Dr Tanay Padgaonkar, Cardiologist at Saifee Hospital Mumbai, told Moneycontrol that high blood pressure does not operate in isolation but interacts with other risk factors such as diabetes, obesity, smoking and high cholesterol level to exponentially hike the risk of CHD. The doctor says that managing blood pressure through lifestyle modification, routine check-ups and correct medication is crucial to long-term heart health.

Also Read: Cardiologist explains who is more at risk of heart attack: Men or women?

To better understand how hypertension contributes to coronary heart disease, let’s explore the key mechanisms through which sustained high blood pressure damages the heart and arteries:

1. The Strain of the Heart Slumbering

When blood pressure is sustained at high levels, the heart muscle, especially the left ventricle is compelled to work harder to push the blood against the high resistance. This leads to left ventricular hypertrophy (LVH) which is the thickening of the heart muscle that is initially beneficial in maintaining the functioning but with time reduces the effectiveness of the heart. The strain predisposes a person to heart failure and ischemic events.

2. Damage to the Arterial Walls

High blood pressure directly damages the fine lining of blood vessels which is called the endothelium. This long-term stress leads to the weakening of arterial walls and increases the progression of atherosclerosis, a condition caused by stiffening and loss of elasticity of the arteries. The small-diameter vessels become less compliant and therefore, the blood is more difficult to move freely to the heart.

3. Hardened Arteries and Cholesterol Deposition

High blood pressure causes the damaged arterial walls that are the perfect environment of the formation of cholesterol deposits and a plaque. These plaques eventually enlarge the lining of the arteries and slow down blood flow. The heart muscle does not get enough oxygen when the coronary arteries are compromised which increases the chances of angina and myocardial infarction significantly.

4. High risk of developing blood clots

Other than accumulation of the plaque, hypertension causes the plaques to be vulnerable and burst. The rupture of a plaque may cause thrombosis (forming a blood clot), which suddenly blocks a coronary artery. This is one of the causes of sudden blockage that is the main cause of acute heart attack.

5. The Vicious Cycle and the Other Risk Factors

Hypertension does not tend to work in isolation. The harmful effects of diabetes are increased by poor lifestyle habits, including smoking, physical inactivity, obesity, and uncontrolled diabetes. As an example, high blood pressure in individuals with metabolic syndrome acts in a synergistic relationship with insulin resistance and dyslipidemia to accelerate the rate of coronary artery damage resulting in a vicious circle of potentially deadly results that hastens the onset of CHD.

Also Read: Truth about heart diseases: 5 common misconceptions about heart health

The pathways between hypertension and coronary heart disease include mechanical stress of the heart, vascular damage, rapid development of plaque, high risk of thrombosis, and interaction with other metabolic conditions. Due to this complex effect, blood pressure management must be effective with lifestyle modifications, drugs and frequent monitoring in the prevention of CHD onset and progression.

FAQs on Hypertension and Coronary Heart Disease:

1. What is hypertension?
Hypertension, or high blood pressure, is a condition where the force of blood against the artery walls is consistently too high, potentially leading to serious health issues.

2. How does hypertension contribute to coronary heart disease?
Sustained high blood pressure damages the arteries, promoting plaque build-up that narrows and hardens the arteries, reducing blood flow to the heart and increasing the risk of CHD.

3. What are common symptoms of hypertension?
Hypertension is often symptomless, earning it the nickname "silent killer." However, some may experience headaches, shortness of breath, or nosebleeds.

4. How can hypertension be managed?
Hypertension can be managed through lifestyle changes (diet, exercise, quitting smoking), regular medical check-ups, and prescribed medications.

5. What are the risk factors for coronary heart disease?
Risk factors include high blood pressure, diabetes, obesity, smoking, high cholesterol, and a sedentary lifestyle.

6. Can hypertension be prevented?
While some risk factors (genetics, age) cannot be controlled, many can be managed through a healthy lifestyle, regular exercise, a balanced diet, and routine medical check-ups.

Disclaimer: This article, including health and fitness advice, only provides generic information. Don’t treat it as a substitute for qualified medical opinion. Always consult a specialist for specific health diagnosis.

Nivedita is a Delhi-based journalist who writes on health, fashion, lifestyle and entertainment. Views expressed are personal.
first published: Sep 26, 2025 10:44 am

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