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HomeScienceTardigrade's protein 'Dsup' offers potential boost to human resilience-Here is what study says

Tardigrade's protein 'Dsup' offers potential boost to human resilience-Here is what study says

Scientists have discovered a tardigrade protein, Dsup, that protects DNA from damage and may enhance human cellular resilience under extreme stress conditions.

November 02, 2025 / 14:14 IST
Researchers Uncover Water Bear Protein That Shields DNA and Cells (Image: Canva)

Tiny water bears survive extremes humans cannot endure naturally. Their secret lies in a protective protein called Dsup. Scientists are exploring applications for medicine and technology.

What Has Been Discovered?

Researchers discovered Dsup, a DNA-protecting protein in tardigrades. This protein shields genetic material from radiation and oxidative stress. It helps tardigrades survive extreme heat, cold and vacuum.

Who and Where Conducted Research?

The study was conducted by teams at Japan and USA. Collaborating universities include Kyoto University and the University of Tokyo. Their research focused on cellular biology and genetic resilience mechanisms.

The international collaboration combined expertise in molecular biology, genetics, and biochemistry. Their joint efforts accelerated understanding of how Dsup protects DNA effectively.

How Did the Research was conducted?

Scientists inserted Dsup protein into human cultured cells in laboratories. They exposed cells to radiation and oxidative stress conditions. Results showed DNA damage was significantly reduced in modified cells.

Further experiments examined how Dsup interacts directly with chromatin structures inside cells. High-resolution imaging revealed it binds DNA and forms a protective, flexible shield. This prevents strand breaks and reduces oxidative damage during extreme stress.

Observations and Implications

Dsup forms a protective shield around the DNA structure. Cells expressing Dsup survive otherwise lethal radiation doses better. Potential applications include cancer therapy, space exploration, and crop resilience. Researchers shared advanced laboratory techniques and data to ensure reproducibility.

Future Research on Water Bears

Researchers aim to understand Dsup’s mechanisms in more detail. They plan to explore safe applications in humans and other organisms. Long-term studies may reveal further cellular protection strategies inspired by tardigrades.

first published: Nov 2, 2025 02:14 pm

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