Wall Street's main indexes opened lower on Wednesday, a day after the Nasdaq scaled a fresh peak, as investors assessed the risk to the domestic economy from a surge in coronavirus cases in several U.S. states.
The Dow Jones Industrial Average fell 163.14 points, or 0.62 percent, at the open to 25,992.96.
The S&P 500 opened lower by 16.89 points, or 0.54 percent, at 3,114.40. The Nasdaq Composite fell 37.55 points, or 0.37 percent, at 10,093.82 shortly after market open.
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