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Vaccine maker Biological E acquires Akorn's injectable plant in India for $10 million

Biological E said the acquisition will enable the Hyderabad-based company to enhance its manufacturing capabilities and supply of its vaccines and injectable medicines.

August 17, 2020 / 15:22 IST
Flu vaccine (Representative Image)

Vaccine maker Biological E (BE), on August 17 said it has acquired Akorn India, a subsidiary of US-based Akorn which manufactures speciality generic injectable medicines and vaccines for $10 million in cash.

BE said the acquisition will enable the Hyderabad-based company to enhance its manufacturing capabilities and capacities to produce and supply its vaccines and injectable medicines.

"BE is in the process of developing a COVID-19 vaccine and may be able to use the facilities at Akorn India Paonta Sahib Plant in Himachal Pradesh for commercial-scale manufacture of the vaccine at the appropriate time," BE said in a statement.

The Akorn India plant in Paonta Sahib, Himachal Pradesh has a fully staffed sterile injectable manufacturing facility with a 39,000 sq. metres of built-up area spread over a 14-acre campus with an annual capacity for about 135 million units with the potential for immediate expansion of a further 30 million units.

“We would leverage BE’s and Akorn India’s capabilities to enhance our supply capacities both in vaccines and in generic injectables," said Mahima Datla, Managing Director of BE.

COVID-19 Vaccine

Frequently Asked Questions

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How does a vaccine work?

A vaccine works by mimicking a natural infection. A vaccine not only induces immune response to protect people from any future COVID-19 infection, but also helps quickly build herd immunity to put an end to the pandemic. Herd immunity occurs when a sufficient percentage of a population becomes immune to a disease, making the spread of disease from person to person unlikely. The good news is that SARS-CoV-2 virus has been fairly stable, which increases the viability of a vaccine.

How many types of vaccines are there?

There are broadly four types of vaccine — one, a vaccine based on the whole virus (this could be either inactivated, or an attenuated [weakened] virus vaccine); two, a non-replicating viral vector vaccine that uses a benign virus as vector that carries the antigen of SARS-CoV; three, nucleic-acid vaccines that have genetic material like DNA and RNA of antigens like spike protein given to a person, helping human cells decode genetic material and produce the vaccine; and four, protein subunit vaccine wherein the recombinant proteins of SARS-COV-2 along with an adjuvant (booster) is given as a vaccine.

What does it take to develop a vaccine of this kind?

Vaccine development is a long, complex process. Unlike drugs that are given to people with a diseased, vaccines are given to healthy people and also vulnerable sections such as children, pregnant women and the elderly. So rigorous tests are compulsory. History says that the fastest time it took to develop a vaccine is five years, but it usually takes double or sometimes triple that time.

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"The timing of this acquisition is fortuitous as it will immediately allow us to expand our capacity to manufacture our investigational COVID-19 vaccine. With these capacities, we would be in a position to offer over 1 billion doses per annum,” BE said in a statement.

BE has recently tied up with Johnson and Johnson to manufacture 400-500 million doses of the latter's COVID-19 vaccine for India and other countries. BE has entered into a licencing agreement with Baylor College of Medicine of the University of Houston, Texas, for the development of COVID-19 vaccine.

Viswanath Pilla
Viswanath Pilla is a business journalist with 14 years of reporting experience. Based in Mumbai, Pilla covers pharma, healthcare and infrastructure sectors for Moneycontrol.
first published: Aug 17, 2020 03:22 pm

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