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Delta variant is "most transmissible" identified so far: WHO

At a press briefing on Friday, WHO director-general Tedros Adhanom Ghebreyesus said the lack of vaccines in poor countries was exacerbating the delta variant's transmission.

June 26, 2021 / 08:14 AM IST

The head of the World Health Organization said the COVID-19 delta variant, first seen in India, is “the most transmissible of the variants identified so far,” and warned it is now spreading in at least 85 countries.

At a press briefing on Friday, WHO director-general Tedros Adhanom Ghebreyesus said the lack of vaccines in poor countries was exacerbating the delta variant's transmission.

He described a recent meeting he attended of an advisory group established to allocate vaccines.

“They were disappointed because there is no vaccine to allocate,” he said, criticizing rich countries for declining to immediately share shots with the developing world. “If there is no vaccine, what do you share?”

Tedros said the global community was failing and risked repeating the mistakes made during the AIDS crisis decades ago and during the 2009 swine flu pandemic — when vaccines only arrived in poor countries after the outbreak ended.

COVID-19 Vaccine

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How does a vaccine work?

A vaccine works by mimicking a natural infection. A vaccine not only induces immune response to protect people from any future COVID-19 infection, but also helps quickly build herd immunity to put an end to the pandemic. Herd immunity occurs when a sufficient percentage of a population becomes immune to a disease, making the spread of disease from person to person unlikely. The good news is that SARS-CoV-2 virus has been fairly stable, which increases the viability of a vaccine.

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There are broadly four types of vaccine — one, a vaccine based on the whole virus (this could be either inactivated, or an attenuated [weakened] virus vaccine); two, a non-replicating viral vector vaccine that uses a benign virus as vector that carries the antigen of SARS-CoV; three, nucleic-acid vaccines that have genetic material like DNA and RNA of antigens like spike protein given to a person, helping human cells decode genetic material and produce the vaccine; and four, protein subunit vaccine wherein the recombinant proteins of SARS-COV-2 along with an adjuvant (booster) is given as a vaccine.

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Vaccine development is a long, complex process. Unlike drugs that are given to people with a diseased, vaccines are given to healthy people and also vulnerable sections such as children, pregnant women and the elderly. So rigorous tests are compulsory. History says that the fastest time it took to develop a vaccine is five years, but it usually takes double or sometimes triple that time.

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“It took 10 years (for antiretrovirals) to reach the low income countries after (HIV) was already rampant in high income countries,” he said. “Do we want to repeat the same thing?”

COVAX, the U.N.-backed effort aiming to distribute vaccines to poor countries, has missed several targets to share COVID-19 shots, and its biggest supplier is not expected to export any vaccines until the end of the year.

The hundreds of millions of doses promised by countries including Britain, the U.S. and others are not likely to arrive anytime soon.

“We have through COVAX this month zero doses of AstraZeneca vaccine, zero doses of Pfizer vaccine, zero doses of (Johnson and Johnson) vaccine,” acknowledged Dr. Bruce Aylward, a senior adviser to the WHO chief.

“Every single one of our suppliers is unable to supply during this period because others are making demands on those products, others who are vaccinating very young populations that are not at risk.”

As border restrictions and other public health measures are loosened across Europe, the U.S. and in other countries with high vaccination rates, WHO officials warned that this could lead to a resurgence of disease.

“The global situation is incredibly fragile,” said Maria Van Kerkhove, the WHO's technical lead on COVID-19.

Van Kerkhove said that while transmission is dropping in Europe, there are numerous events — from large sporting events to backyard barbeques — that all have consequences for disease spread.

“The delta variant, the virus, will continue to evolve," Van Kerkhove said.

"Right now our public health and social measures work, our vaccines work, our diagnostics work, our therapeutics work. But there may be a time where this virus evolves and these countermeasures don't.”

Earlier this month, British officials announced that they would allow 60,000 fans to attend the semi-finals and finals of the European football championships at London's Wembley stadium — to the dismay of some public health experts.

Lawrence Young, a virologist at the University of Warwick, called it “worrying and confusing,” saying there was limited data to prove its safety, especially given the prevalence of the more infectious delta variant.

”(The) inevitable opportunities for the virus to spread in enclosed spaces like lavatories is a recipe for disaster."

PTI
first published: Jun 26, 2021 08:14 am