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Stealth Omicron: What we know about the new Covid subvariant sneaking into countries

The subvariant has also been dubbed 'stealth Omicron' because it is difficult to detect.

March 22, 2022 / 19:37 IST
People queue for a COVID-19 test in Times Square as the Omicron coronavirus variant continues to spread in Manhattan, New York City. (File)

A subvariant of Omicron has been rapidly spreading in the US, parts of Europe and some parts of Asia that has been dubbed ‘stealth Omicron’ because it is difficult to detect. The new subvariant has been categorised under Omicron as BA2 for now.

Subvariant BA2 appears to be transmissible than BA1, the World Health Organisation has said adding that even though there is a spike in sequences in the new subvariant, global cases of all coronavirus variants have declined.

Although called a variant of concern, WHO has said the new subvariant will be categorized under Omicron and should not yet be considered to be a separate variant.

“BA.2 differs from BA.1 in its genetic sequence, including some amino acid differences in the spike protein and other proteins. Studies have shown that BA.2 has a growth advantage over BA.1. Studies are ongoing to understand the reasons for this growth advantage, but initial data suggest that BA.2 appears inherently more transmissible than BA.1, which currently remains the most common Omicron sublineage reported. This difference in transmissibility appears to be much smaller than, for example, the difference between BA.1 and Delta,” WHO said in a statement explaining the differences between Omicron and the new subvariant.

White House Chief Medical Advisor Dr Anthony Fauci, a top expert in the Covid-19 disease, has also said the subvariant may account for around 30 percent of all new infections in the US. It is currently the most dominant variant in the country as well.

COVID-19 Vaccine

Frequently Asked Questions

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How does a vaccine work?

A vaccine works by mimicking a natural infection. A vaccine not only induces immune response to protect people from any future COVID-19 infection, but also helps quickly build herd immunity to put an end to the pandemic. Herd immunity occurs when a sufficient percentage of a population becomes immune to a disease, making the spread of disease from person to person unlikely. The good news is that SARS-CoV-2 virus has been fairly stable, which increases the viability of a vaccine.

How many types of vaccines are there?

There are broadly four types of vaccine — one, a vaccine based on the whole virus (this could be either inactivated, or an attenuated [weakened] virus vaccine); two, a non-replicating viral vector vaccine that uses a benign virus as vector that carries the antigen of SARS-CoV; three, nucleic-acid vaccines that have genetic material like DNA and RNA of antigens like spike protein given to a person, helping human cells decode genetic material and produce the vaccine; and four, protein subunit vaccine wherein the recombinant proteins of SARS-COV-2 along with an adjuvant (booster) is given as a vaccine.

What does it take to develop a vaccine of this kind?

Vaccine development is a long, complex process. Unlike drugs that are given to people with a diseased, vaccines are given to healthy people and also vulnerable sections such as children, pregnant women and the elderly. So rigorous tests are compulsory. History says that the fastest time it took to develop a vaccine is five years, but it usually takes double or sometimes triple that time.

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Fauci, speaking on ABC network, said that vaccines and booster shots will help prevent serious illness adding that even if the virus is not as severe, it may cause a worrying uptick in cases in the US in the coming months.

While Omicron is highly transmissible, the disease has not been severe so far. However, the new subvariant is being detected frequently. WHO said they will be monitoring the subvariant closely.

Stella Dey
first published: Mar 22, 2022 07:34 pm

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