Indian researchers discovered no indication linking Covid-19 vaccination to "unexplained sudden deaths," according to a statement from a medical organization on November 21. Instead, the Indian Council of Medical Research (ICMR) attributed the occurrences to the disease itself, along with factors such as binge drinking and intense exercise.
The ICMR conducted a study in response to "anecdotal reports about sudden unexplained deaths among apparently healthy adults" aged 18 to 45 between October 2021 and March 2023. The research group published their findings in the Indian Journal of Medical Research, stating, "We found no evidence of a positive association of COVID-19 vaccination with unexplained sudden death among young adults."
Simultaneously, the study identified risk factors for unexplained sudden death, including a family history of sudden death, hospitalization for COVID-19, and lifestyle behaviors such as recent binge drinking and vigorous-intensity physical activity.
In their investigation, ICMR researchers examined 29,171 sudden deaths, reviewing records of 729 cases and 2,916 "control" subjects. Government data shows India suffered 45 million (4.5 crore) Covid infections and 533,295 related deaths but experts say the actual numbers are several times higher. During the peak of the Covid crisis, many Indian hospitals faced bed shortages, leading to numerous deaths occurring at home.
The primary objective of vaccination remains the prevention of severe COVID-19 outcomes. While adverse events, particularly thromboembolic (obstruction of blood vessel) events, have been documented post-COVID-19 vaccination, limited evidence suggests protection against all-cause mortality across various age groups.
Beyond COVID-19-specific factors, the research identified two lifestyle-related high-risk behaviors associated with unexplained sudden death. Binge drinking within 48 hours before death and engaging in unaccustomed, vigorous, and intense physical activity within the same timeframe. The exertion involved in intense physical exercise is recognized for elevating the risk of acute plaque rupture, leading to partial or complete blockage of coronary arteries and ultimately resulting in sudden death.
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