Breast cancer occurs when abnormal cells grow in the breast, often forming a tumour. According to the National Cancer Institute (NCI), it starts in the breast tissues, usually in the ducts or lobules. Each breast has 50 to 20 lobes,made up of lobules and milk producing bulbs. These are all connected by ducts. Most breast cancer begin in these ducts or lobules, where cells are more active and prone to change.
Women are born with a set number of eggs, and certain cancer treatments, including chemotherapy and hormone therapy, can damage or reduce that egg supply.
Also read: Ileana D’Cruz on her struggle with breastfeeding: ‘I had no idea it was going to be intensely painful…’Dr Karishma Kirti, Consultant Breast Specialist and Oncoplastic Surgeon, informs, “The ovaries are very sensitive during cancer treatment, and once eggs are lost, they can’t be replaced,” She adds that with the right steps taken early, women don’t have to give up their dream of becoming a mother.
Not every treatment will affect fertility the same way. The risks, says Dr Kirti, depend on your age, the type and dose of chemotherapy, and whether long-term hormone therapy (like tamoxifen) is needed. “Younger women usually have more eggs and can sometimes recover better after treatment, but timing is everything,” Talking to your doctor about fertility before treatment starts gives you more options and better outcomes.
Options to preserve fertility: Dr Kirti suggests three main ways doctors can help protect your fertility during breast cancer treatment:Egg or embryo freezing: This is the most common and proven method. Here’s how, Dr Kirti suggests, it works:
Ovarian suppression: This involves taking hormone injections that temporarily switch off your ovaries during chemotherapy. “The idea is to protect your eggs by keeping your ovaries inactive. It’s not 100% effective, but it can be used alongside egg freezing to add another layer of protection,” she says.
Ovarian tissue freezing: Still considered experimental, this method involves removing and freezing a small piece of your ovary before treatment. “Later, it might be reimplanted to try to restore fertility. This option is helpful if there’s no time to go through the egg freezing process before treatment begins,” informs Dr Kirti.
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