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COVID-19 fourth wave in India might set in around June 22 and last for 4 months: IIT-K researchers

However, the severity of the wave, they said, will depend on the emergence of new variants, vaccination status, and administration of booster doses.

February 27, 2022 / 11:16 AM IST
A man with breathing problem is wheeled inside a COVID-19 hospital for treatment during the ongoing coronavirus disease in Ahmedabad. (Representative image: Reuters)

A man with breathing problem is wheeled inside a COVID-19 hospital for treatment during the ongoing coronavirus disease in Ahmedabad. (Representative image: Reuters)

Even as the third wave of the coronavirus pandemic in India is on a decline, researchers from the Indian Institute of Technology Kanpur (IIT-K) have predicted that the fourth wave may set in around June 22 and continue till October 24. However, the severity of the wave, they said, will depend on the emergence of new variants, vaccination status, and administration of booster doses.

The IIT-K researchers predicted that if there is a fourth wave, it will go on at least for four months, the Times of India reported. The statistical prediction has been published on the preprint server MedRxiv on February 24. According to their paper, the curve will peak sometime around August 15 to 31 and decline thereafter.

Predictions by the researchers have reportedly been near accurate during the last three times, with a deviation of only a few days. The team, conducted by the Sabara Parshad Rajeshbhai, Subhra Sankar Dhar and Shalabh of the department of mathematics and statistics of IIT-K, used a statistical model for their prediction and said that the fourth wave in India may arrive 936 days after the initial available date of the Covid-19 outbreak (January 30, 2020).

“Therefore, the fourth wave (presumed) starts from June 22, reaching its peak on August 23 and ending on October 24,” they said. The team used a methodology called “Bootstrap” to compute the confidence interval of the time point of the peak of a fourth wave. According to the researches, the method can also be used to forecast a fourth and other waves in other countries as well.

The researches started working on the fourth wave prediction motivated by the accuracy of the third wave forecast done using a mixture of Gaussian distribution based on the data on Zimbabwe.

COVID-19 Vaccine

Frequently Asked Questions

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How does a vaccine work?

A vaccine works by mimicking a natural infection. A vaccine not only induces immune response to protect people from any future COVID-19 infection, but also helps quickly build herd immunity to put an end to the pandemic. Herd immunity occurs when a sufficient percentage of a population becomes immune to a disease, making the spread of disease from person to person unlikely. The good news is that SARS-CoV-2 virus has been fairly stable, which increases the viability of a vaccine.

How many types of vaccines are there?

There are broadly four types of vaccine — one, a vaccine based on the whole virus (this could be either inactivated, or an attenuated [weakened] virus vaccine); two, a non-replicating viral vector vaccine that uses a benign virus as vector that carries the antigen of SARS-CoV; three, nucleic-acid vaccines that have genetic material like DNA and RNA of antigens like spike protein given to a person, helping human cells decode genetic material and produce the vaccine; and four, protein subunit vaccine wherein the recombinant proteins of SARS-COV-2 along with an adjuvant (booster) is given as a vaccine.

What does it take to develop a vaccine of this kind?

Vaccine development is a long, complex process. Unlike drugs that are given to people with a diseased, vaccines are given to healthy people and also vulnerable sections such as children, pregnant women and the elderly. So rigorous tests are compulsory. History says that the fastest time it took to develop a vaccine is five years, but it usually takes double or sometimes triple that time.

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first published: Feb 27, 2022 11:16 am