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HomeNewsWorldNo need for Omicron-specific boosters currently: Anthony Fauci

No need for Omicron-specific boosters currently: Anthony Fauci

"Our booster vaccine regimens work against Omicron. At this point, there is no need for a variant-specific booster," Fauci told reporters at a White House briefing.

December 16, 2021 / 08:44 IST
Dr Anthony Fauci (Image Source: Reuters)

Booster doses of currently available COVID-19 vaccines work against the Omicron variant of the coronavirus and there appears to be no need for variant-specific boosters, top U.S. infectious disease expert Anthony Fauci said.

"Our booster vaccine regimens work against Omicron. At this point, there is no need for a variant-specific booster," Fauci told reporters at a White House briefing.

He said the neutralizing activity of two doses of Moderna's

COVID-19 vaccine is "substantially low" against Omicron, citing data from the National Institute of Allergy and Infectious Diseases, of which he is director.

"However, if you look at two weeks post the third dose, note the substantial degree of elevation of the neutralizing title; well within the range of neutralizing Omicron," he said of the study's findings, on which Moderna collaborated with the NIAID.

COVID-19 Vaccine

Frequently Asked Questions

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How does a vaccine work?

A vaccine works by mimicking a natural infection. A vaccine not only induces immune response to protect people from any future COVID-19 infection, but also helps quickly build herd immunity to put an end to the pandemic. Herd immunity occurs when a sufficient percentage of a population becomes immune to a disease, making the spread of disease from person to person unlikely. The good news is that SARS-CoV-2 virus has been fairly stable, which increases the viability of a vaccine.

How many types of vaccines are there?

There are broadly four types of vaccine — one, a vaccine based on the whole virus (this could be either inactivated, or an attenuated [weakened] virus vaccine); two, a non-replicating viral vector vaccine that uses a benign virus as vector that carries the antigen of SARS-CoV; three, nucleic-acid vaccines that have genetic material like DNA and RNA of antigens like spike protein given to a person, helping human cells decode genetic material and produce the vaccine; and four, protein subunit vaccine wherein the recombinant proteins of SARS-COV-2 along with an adjuvant (booster) is given as a vaccine.

What does it take to develop a vaccine of this kind?

Vaccine development is a long, complex process. Unlike drugs that are given to people with a diseased, vaccines are given to healthy people and also vulnerable sections such as children, pregnant women and the elderly. So rigorous tests are compulsory. History says that the fastest time it took to develop a vaccine is five years, but it usually takes double or sometimes triple that time.

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BioNTech and Pfizer said last week that a three-shot course of their vaccine was able to neutralize Omicron in a laboratory test, but two doses resulted in significantly lower neutralizing antibodies.

J&J has yet to release any of its own data about how its vaccine performs against the new coronavirus strain.

All three U.S.-authorized COVID-19 vaccines appear to be significantly less protective against Omicron in laboratory testing, but a booster dose likely restores most of the protection, according to a study published on Tuesday.

There are confirmed cases of the variant in at least 36 states, representing about 3% of COVID-19 cases in the country, U.S. Centers for Disease Control and Prevention Director Rochelle Walensky said at the same briefing. The Delta variant remains responsible for the vast majority of cases, she added.

"We expect to see the proportion of Omicron cases here in the United States continue to grow in the coming weeks. Early data suggests that Omicron is more transmissible than Delta, with a doubling time of about two days," Walensky said.

She said officials were starting to see COVID-19 cases increase in fully vaccinated nursing-home residents, but residents who have had a booster shot have an infection rate that is 10 times lower.

Reuters
first published: Dec 16, 2021 08:44 am

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