Revenue is expected to have slipped 5 percent, hurt by lower memory-chip shipments.
Launching the Note 9 at 11 a.m. in New York, or Friday midnight in Seoul, Samsung also announced partnerships with global hit game Fortnite and music-streaming service Spotify Technology SA in a stepped-up challenge to Apple Inc in the premium-phone race.
While a stronger won and falling NAND chip prices could take some shine off the performance, most analysts are tipping a strong quarter for the world's leading maker of semiconductors, smartphones and televisions.
Samsung Electronics Co Ltd said on Wednesday it would create an artificial intelligence (AI) research centre and strengthen an executive role to look for new business areas for all its three major business groups.
The appointment, which Samsung announced on Thursday, came after former CFO Lee Sang-hoon stepped down from the role two days ago after being nominated Samsung's next chairman of the board.
Its parent company in May secured permission from South Korean authorities to test a self-driving car fitted with its own sensors and software systems. At that time, South Korean officials said the company planned to use the car to develop a self-driving car algorithm that could drive in adverse weather.
The South Korean tech giant said in a regulatory filing that it approved on Monday $2.3 billion out of the $7 billion in expected investment.
The world's biggest maker of memory chips, smartphones and television sets is widely expected to break profit records for the full year, as better-than-forecast performance in its mobile business lifted quarterly operating profit slightly above its early-July guidance, analysts said.
The Apple Inc smartphone rival and global memory chip leader said second-quarter operating profit was likely 14 trillion won (9 billion pounds), compared with the 13.1 trillion won average of 19 analyst estimates in a Thomson Reuters poll.
The world's biggest memory chip maker by revenue said the spending includes 14.4 trillion won by 2021 on its new NAND factory in Pyeongtaek. It will invest 6 trillion won in a new semiconductor production line in Hwaseong, but did not elaborate on timing or product.
Huawei, the world's No. 3 smartphone maker behind Apple Inc and Samsung Electronics Co Ltd, said net profit rose to 37.1 billion yuan ($5.3 billion)
Samsung's Note 7s were permanently scrapped in October following a global recall, roughly two months from the launch of the near-$900 devices, after some phones self-combusted.
Investors had expected the global leader in smartphones and memory chips to adopt a holding company structure, as the founding Lee family tries to solidify its control of the Samsung Group flagship ahead of a leadership succession.
Samsung had said in November it plans to nominate at least one new board member with "global C-Suite experience" for this year's shareholder meeting as part of its efforts to improve corporate governance. The company said on Friday its search for nominees are continuing.
Wrapping up its months-long probe, the world's top smartphone maker said faulty batteries from two suppliers were to blame for a product failure that wiped USD 5.3 billion off its operating profit.
The world's biggest smartphone maker is seeking to put behind it one of the biggest product safety failures in tech history as it prepares to launch the Galaxy S8, one of its flagship phones, sometime in the first half of this year.
The South Korean firm said in October it was examining all aspects of the phone, suggesting there may be a combination of factors that contributed to one of the costliest product safety failures in tech history.
The executive, in a New Year's speech to Samsung employees disclosed by the firm, also warned of growing political and economic uncertainties from risks such as trade protectionism and foreign exchange rates.
Under pressure from US activist hedge fund Elliott Management, the world's top maker of smartphones, memory chips and televisions said on Tuesday it planned to return 50 percent of its free cashflow in 2016 and 2017 and offered a 36 percent rise in total 2016 dividends.
Samsung said in a statement a tech product launching early next year will use chips made with its 10-nanometre production technology without specifying the device.
The South Korean tech giant said in a statement it expected the blow to profit to be in the mid-2 trillion won range in the October-December period and about 1 trillion won (USD 900 million) for the first quarter of 2017.
Samsung, in a regulatory filing, also cut its July-September revenue estimate to 47 trillion won from the 49 trillion won it guided for last week.
The world's top smartphone maker on Tuesday said it permanently halted sales of the beleaguered flagship smartphone in what could be one of the costliest product safety failures in tech history.
Samsung announced on September 2 a recall of at least 2.5 million Galaxy Note 7 smartphones in 10 markets, including South Korea, due to a faulty battery causing the phones to catch fire, offering refunds or replacement devices using safe batteries.
Investors had wiped 15.9 trillion won (14.3 billion) off the South Korean firm's market capitalisation as of 0303 GMT, as a series of warnings from regulators and airlines around the world raised fears for the future of the flagship device.