Subscribe to PRO at just Rs.33 per month. Use code SUPERPRO
you are here: HomeNewsIndia
Last Updated : Jul 18, 2020 07:04 PM IST | Source: PTI

Child patients in Delhi exhibit Kawasaki-like syndrome, COVID link suspected

Pediatric experts at a leading hospital here said in nearly fifty percent of these cases, patients become "more serious" than those suffering from regular Kawasaki disease.


Some Delhi hospitals are treating young patients, mostly children, who have been exhibiting symptoms of Kawasaki-like syndrome and there is presumably a link with COVID-19, doctors have said.

Pediatric experts at a leading hospital here said in nearly fifty percent of these cases, patients become "more serious" than those suffering from regular Kawasaki disease.

Kawasaki disease is an illness with an unknown cause that leads blood vessels to become inflamed. It affects children, mostly aged below five.


"In the past few months, particularly in the last six weeks, we have received patients who exhibited Kawasaki-like syndrome. There is a presumed link of this to past COVID cases, as either some of these patients were found to be COVID-positive or with antibodies in response to the disease," said Dr Dhiren Gupta, Senior Consultant, pediatrics department at the Sir Ganga Ram Hospital (SGRH) here.

COVID-19 Vaccine

Frequently Asked Questions

View more
How does a vaccine work?

A vaccine works by mimicking a natural infection. A vaccine not only induces immune response to protect people from any future COVID-19 infection, but also helps quickly build herd immunity to put an end to the pandemic. Herd immunity occurs when a sufficient percentage of a population becomes immune to a disease, making the spread of disease from person to person unlikely. The good news is that SARS-CoV-2 virus has been fairly stable, which increases the viability of a vaccine.

How many types of vaccines are there?

There are broadly four types of vaccine — one, a vaccine based on the whole virus (this could be either inactivated, or an attenuated [weakened] virus vaccine); two, a non-replicating viral vector vaccine that uses a benign virus as vector that carries the antigen of SARS-CoV; three, nucleic-acid vaccines that have genetic material like DNA and RNA of antigens like spike protein given to a person, helping human cells decode genetic material and produce the vaccine; and four, protein subunit vaccine wherein the recombinant proteins of SARS-COV-2 along with an adjuvant (booster) is given as a vaccine.

What does it take to develop a vaccine of this kind?

Vaccine development is a long, complex process. Unlike drugs that are given to people with a diseased, vaccines are given to healthy people and also vulnerable sections such as children, pregnant women and the elderly. So rigorous tests are compulsory. History says that the fastest time it took to develop a vaccine is five years, but it usually takes double or sometimes triple that time.

View more

According to him, this is part of an emerging disease called 'multi-system inflammatory syndrome' or the MIS, which stared in the UK and cases were also reported by the Centre for Disease Control (CDC) in the US.

"In India, such trends were seen first in Mumbai and now in Delhi too. In half of the cases, it is more fulminant or serious than a regular case of Kawasaki," Dr Gupta said.

He said "there is a link" with COVID-19 and that in some cases the antibodies react and cause problems.

The SGRH has seen six such cases with Kawasaki-like syndrome. While four such patients got discharged, a two-year-old is in the ICU at the moment and a four-year-old in the ward.

At Kalawati Saran Children's Hospital attached to the Lady Hardinge Medical College (LHMC), doctors said there were five to six cases in which children treated in COVID areas and COVID suspect areas had symptoms like those of the Kawasaki disease in which the blood vessels become inflammed throughout the body.

"There could be other reasons behind the ailment, but as we are facing the COVID-19 pandemic, the disease most likely is related to the novel coronavirus infection,” said N N Mathur, Medical Director of the LHMC.

Doctors said the symptoms of Kawasaki syndrome are fever for 3-5 days and redness of eyes and lips.

In serious cases that have been presented at hospitals, the fever could last longer, blood pressure drops, and there is change in echocardiogram patterns, they said.
First Published on Jul 18, 2020 06:54 pm