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Exercise in your 50s and 60s to keep your memory sharp, reduce dementia risk by 40%

How to keep brain sharp: A recent research published in JAMA network reminds us that lifestyle choices matter, not just when young, but across our adult life. If you’re over 40, it isn’t too late. Those evening strolls, weekend gardening, playing with kids or grandkids, or simply staying on your feet, they all count.
December 02, 2025 / 14:16 IST
According to the study, people who stay physically active in midlife or later life have a meaningfully lower risk of dementia when they get older (Image: Pexels)

If you’ve ever wondered whether those brisk walks, weekend chores or garden pottering really make a difference, know that they just might keep your brain sharper as you age.

A major piece of the long-running Framingham Heart Study, that has been observing families for generations, has found that people who stay physically active in midlife or later life have a meaningfully lower risk of dementia when they get older.

The results of the study show that people  who moved the most in their 40s, 50s and 60s had about a 40 percent drop in dementia risk compared with people who barely budged. Those who kept active in their later years did even better.

Also read | 9 smart ways to keep brain sharp: Backward walking, cold showers

Nevertheless, being active in your twenties and early thirties didn’t seem to change much at all. The study suggests the magic window for protecting your brain might be middle age and beyond, not the early, carefree years when you could sprint for the bus without pulling something.

None of this means you need to run marathons or buy fancy outfits. In fact, the researchers considered all sorts of movement, walking the dog, doing the hoovering, climbing stairs, mowing the lawn, or even getting stuck into a proper tidy-up. It all added up.

Also read | 7 everyday habits that protect your brain from dementia

Health benefits of daily exercises

Here’s why timing matters and what a study published in JAMA network shows:

  • For people whose activity levels in their midlife (roughly ages 45–64) ranked among the highest, the risk of developing dementia later was about 41 percent lower compared to those with minimal activity.
  • Among those active in late life (around ages 65 and above), the dementia risk was lowered by about 45 percent for the fittest individuals.
  • Early-adult activity (ages 26–44) did not show a meaningful link to dementia risk down the road. The reduced risk applied not only to general dementia, but also to dementia due to Alzheimer-type disease.

FAQS on Dementia

1. How can physical activity impact dementia risk?

Regular physical activity in midlife or later life can lower the risk of dementia by up to 45%, as shown by the Framingham Heart Study.

2. Which age group benefits most from exercise in terms of dementia prevention?

Individuals active in their 40s, 50s, and 60s had significantly reduced dementia risk, with a 40% lower chance compared to those who were inactive.

3. Does early adulthood physical activity affect dementia risk?

The study found no significant link between physical activity in early adulthood (ages 26–44) and dementia risk later in life.

4. What types of physical activities are beneficial for brain health?

All types of movement, including walking, chores, gardening, and climbing stairs, contribute to reduced dementia risk.

5. Is it necessary to engage in vigorous exercise to protect against dementia?

No, even moderate activities like walking the dog or doing household chores can help reduce dementia risk.

Disclaimer: This article, including health and fitness advice, only provides generic information. Don’t treat it as a substitute for qualified medical opinion. Always consult a specialist for specific health diagnosis.

Namita S Kalla is a senior journalist who writes about different aspects of modern life that include lifestyle, health, fashion, beauty, and entertainment.
first published: Dec 2, 2025 02:16 pm

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