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Vitamin B12 deficiency in men over 50: 8 secret signs affecting legs, feet, and sleep

Vitamin B12 is essential for maintaining brain function, nerve health, and heart health. As men age, their ability to absorb vitamin B12 decreases, making the deficiency more common after 50. At night, this deficiency may show up as unusual symptoms like strange walking and influence movement of feet, comfort, and sleep. Recognizing these signs early is key to preventing long-term nerve damage and ensuring a better quality of life.

August 18, 2025 / 11:56 IST
Strange nighttime leg and foot symptoms could be an early warning of Vitamin B12 deficiency in men over 50. Don’t ignore the signs. (Image: Pexels)

There are several reasons why vitamin B12 is essential for men as they grow older. First, it supports brain health and cognitive function, helping reduce memory loss and lowering the risk of neurodegenerative diseases such as Alzheimer’s.

Second, vitamin B12 plays a key role in red blood cell production and DNA synthesis, which are vital for energy and overall vitality needed to live a healthy life. Since absorption of B12 tends to decrease in men as they age; therefore, modifying supplementation or the diet becomes important.

Additionally, B12 is also critical for heart health as it lowers homocysteine levels—a known risk factor for heart disease. It also contributes to nerve health, preventing neuropathic pain, balance issues, and mobility challenges. Overall, maintaining healthy B12 levels will increase quality of life overall, supporting physical and mental functions during the golden years so that we can live our lives with independence and vigor.

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Eight Weird Legs And Feet At Night Symptoms Of Vitamin B12 Deficiency In Men In Their 50s

• Numbness and Tingling: The sensation of numbness and the feeling of tingling in the legs and feet may also indicate nerve damage from the Vitamin B12 deficiency. That pins and needles sensation often comes on at night when resting and can be more pronounced. As vitamin B12 is the key nutrient to keep the nerve cells healthy and functional, this symptom appears, explains Dr Mayank Kushwaha from Felix Hospital, Delhi-NCR.

• Muscle Weakness: If a man in his 50s is B12 deficient, he might start to see some gradual loss of strength, especially in the legs. This can make it challenging to do things like walking or going up stairs. Sub-optimal Vitamin B12 can cause muscle weakness, as this vitamin is required for energy production and quick muscle repair.

• Balance Problems: A high degree of imbalance and lack of coordination (especially at night) could be indicative of nerve damage because of long-term Vitamin B12 deficiency. This can lead to an unsteady gait at times. Vitamin B12 is important for the maintenance of the protective sheath around nerves known as the myelin sheath; a deficiency can interfere with the transmission of signals through nerves and cause loss of balance.

Restless Legs Syndrome (RLS): An irresistible need to move the legs, frequently accompanied by unpleasant sensations, can be more severe at night, disrupting sleep.

Doctor Kushwaha says, Vitamin B12 deficiency can also be connected with RLS, because this vitamin plays a major role in nerve health and neurotransmitter function, which are essential for muscle control and movement.

• Burning sensation: A burning sensation in the feet, especially at night, can be a symptom of low Vitamin B12 levels related to peripheral neuropathy. This is the feeling of nerve damage, as Vitamin B12 is a key vitamin for the health of your nerves. Insufficient B12 causes nerves to be damaged, giving rise to pain and burning sensations.

• Pain in the Legs: Softer pain or discomfort in the legs, which may get worse at night, can indicate nerve injury brought on by B12 deficiency. You can experience this kind of pain from mild to painful, which affects activities. Inadequate levels of vitamin B12 can result in degeneration of nerves and may lead to chronic pain and irritation in the legs.

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• Cold Feet: Feeling cold in the feet, even in warming conditions, is a sign of poor circulation and indicates nerve issues due to a low level of B12. According to the doctor, it is essential for forming red blood cells, and low levels can cause anaemia and poor blood circulation, so the feet feel cold.

• Disruption of Sleep: If you experience leg cramps or spasms often at night, sleep may be disrupted since it is related to the absence of Vitamin B12. This vitamin is needed for muscle function and relaxation, and not having enough can lead to muscle spasms, which can cause interruption in sleep and fatigue.

In the case that any of these symptoms are around, then make certain to see your medical care provider so you can get the proper diagnosis as well as treatment.

Disclaimer: This article, including health and fitness advice, only provides generic information. Don’t treat it as a substitute for qualified medical opinion. Always consult a specialist for specific health diagnosis.

Nivedita is a Delhi-based journalist who writes on health, fashion, lifestyle and entertainment. Views expressed are personal.
first published: Aug 18, 2025 11:52 am

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