Roche Holding AG joined peers in striking a cautious note on 2011 as it also grapples with US healthcare reforms and a push in Europe for lower drug prices.
The world's largest maker of cancer drugs, which is looking to cut costs after a string of product setbacks, just fell short of forecasts with a 4% rise in core earnings per share for 2010 as sales growth of top-selling cancer drug Avastin waned.
In local currencies, earnings rose 10%.
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