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Have fever, running nose and cough? Know the difference between Adenovirus, H3N2 and Covid

A cocktail of viruses is spreading through India, and it is difficult to differentiate between the overlapping symptoms of these infections. Here's what you need to know about adenovirus, H3N2 and Covid-19 strains

March 19, 2023 / 14:22 IST
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The general consensus among the medical community regarding viral infections is to take rest and have plenty of fluids. (Image: Pixabay)

As India grapples with a severe H3N2 outbreak, a spike in adenovirus cases across Indian states, particularly in West Bengal, has led to a double whammy, or rather, a triple whammy if one were to consider an increase in Covid-19 infections. A subtype of influenza A strain is driving a surge in H3N2 cases in India, with three deaths reported so far and a total of 451 cases as of March 5. Meanwhile, the adenovirus outbreak in Bengal is more lethal—19 children have died so far and several are hospitalised, with some even admitted to the ICU. With 524 fresh Covid cases also being reported, the Indian Medical Association has sprung into action with task forces on standby.

“Adenovirus is far more virulent and lethal than H3N2 and Covid,” says Dr Rashmi Khadapkar, senior research scientist at SRL Diagnostics. “The current strain is more virulent in children and the mortality rate is between 20-50 per cent. Out of 100+ strains of adenovirus, 6 types are known to cause more serious infections and even lead to death. They are types 3, 4, 7, 8, 14 and 55,” she says. As per reports, adenovirus type 3 and 7 are behind the surge in infections in Bengal. “Type 14 is the most lethal one but as of now, type 3 and 7 are driving the surge in infections in India,” she adds.

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Moneycontrol spoke to infectious disease experts across the country to know from them how one can differentiate between Adenovirus, H3N2 and Covid-19 infections.

Symptoms: The differentiating factor

COVID-19 Vaccine
Frequently Asked Questions

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How does a vaccine work?

A vaccine works by mimicking a natural infection. A vaccine not only induces immune response to protect people from any future COVID-19 infection, but also helps quickly build herd immunity to put an end to the pandemic. Herd immunity occurs when a sufficient percentage of a population becomes immune to a disease, making the spread of disease from person to person unlikely. The good news is that SARS-CoV-2 virus has been fairly stable, which increases the viability of a vaccine.

How many types of vaccines are there?

There are broadly four types of vaccine — one, a vaccine based on the whole virus (this could be either inactivated, or an attenuated [weakened] virus vaccine); two, a non-replicating viral vector vaccine that uses a benign virus as vector that carries the antigen of SARS-CoV; three, nucleic-acid vaccines that have genetic material like DNA and RNA of antigens like spike protein given to a person, helping human cells decode genetic material and produce the vaccine; and four, protein subunit vaccine wherein the recombinant proteins of SARS-COV-2 along with an adjuvant (booster) is given as a vaccine.

What does it take to develop a vaccine of this kind?

Vaccine development is a long, complex process. Unlike drugs that are given to people with a diseased, vaccines are given to healthy people and also vulnerable sections such as children, pregnant women and the elderly. So rigorous tests are compulsory. History says that the fastest time it took to develop a vaccine is five years, but it usually takes double or sometimes triple that time.
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