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Bone pain after sprain or fracture? 6 warning signs of CRPS explained by orthopedic surgeon

An ongoing, intense pain, after an injury has healed, could be a sign of complex regional pain syndrome (CRPS). This nerve condition is often misdiagnosed and can affect mobility, daily function, and quality of life. Here’s what you need to know about CRPS symptoms and treatment:

October 17, 2025 / 13:31 IST
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Don’t ignore persistent bone pain after a sprain or fracture—learn why early detection of CRPS is crucial for effective treatment. (Image: Canva)

The ache that lingers long after a sprain, fracture, or surgery often gets brushed aside as “normal recovery”. But what if that pain doesn’t go away? For some, it worsens with time; burning, stabbing, and affecting daily life. This could be more than a slow recovery. It might be Complex Regional Pain Syndrome (CRPS), a condition that's more common than we think, especially among women over 40. However, it is treatable, if caught early.

CRPS is a rare but serious neurological condition where pain persists in an arm, leg, hand, or foot, often long after the original injury has healed. It can result from changes in the brain, spinal cord, or peripheral nerves. According to Dr Paneendra, Consultant Orthopaedic Surgeon, Apollo Spectra Hospital, Chennai, told Moneycontrol,  many patients, especially women in their 40s and 50s, who suffer for months before realising their pain is not normal. “CRPS can start after something as common as a sprained ankle or fractured wrist.”

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Also read: Orthopedic and spine surgeon shares 5 most common spine problems and tips to prevent them

Dr Paneendra talks about the two types of CRPS, the symptoms, and treatment options:

Types of CRPS:


In both types, the pain is usually disproportionate to the injury and can include strange symptoms like skin colour changes, temperature shifts, swelling, and even nail or hair growth changes.