New COVID-19 variant 'of concern' found in 18 states, says health ministry

What does the data show?

- E484Q and L452R mutations

>> Analysis of samples from Maharashtra showed an increase in the fraction of samples with the E484Q and L452R mutations compared to December 2020. These mutations “confer immune escape and increased infectivity” and were found in 15-20 percent samples, as per the statement.

>> Notably, these mutation samples do not match any previously catalogued VOCs and while these have been categorised as such, they require that states and UTs undertake epidemiological and public health response of “increased testing, comprehensive tracking of close contacts, prompt isolation of positive cases and contacts, and treatment, as per the National Treatment Protocol.”

- N440K mutations

>> From Kerala, of the 2,032 samples sequenced from all 14 districts, the N440K variant (associated with immune escape) has been found in 123 samples from 11 districts.

>> The N440K variant was earlier found in 33 percent samples from Andhra Pradesh, and in 53 of 104 samples from Telangana; and has also been reported from 16 other countries including Australia, Denmark, Japan, Singapore, and the United Kingdom.

>> As of now these can be at best said to be variant under investigation.

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- New double mutant variant found in India

>> The Health Ministry said that though VOCs and a new double mutant variant have been found in India, these have not been detected in numbers sufficient to either establish or direct relationship or explain the rapid increase in cases in some states.

>> Genomic sequencing and epidemiological studies are ongoing to analyse the situation.

What is INSACOG?

It is a grouping of 10 National Laboratories established by MoH&FW on December 25, 2020, to carry out genomic sequencing and analysis of circulating COVID-19 viruses and correlating epidemiological trends with genomic variants.

So far, genome sequencing and analysis have been carried out on samples from arriving international travellers, contacts of those positive for VOC, and community samples from most states at INSACOG’s 10 partner laboratories.

Also Read | Over 5 crore COVID-19 vaccine doses administered in India so far

COVID-19 status in India

Wednesday, 24 March marks a year of India's nationwide lockdown. The country went in for the strict Covid-19 lockdown when just around 525 positive infections were detected. A year on, since the country went into a lockdown, it is facing a second wave of the coronavirus pandemic. The last few days have particularly been troubling for reviving the concerns over possible restrictions and return of another national-level lockdown.

India recorded 47,262 fresh coronavirus cases in a day, the highest single-day rise so far this year, taking the nationwide COVID-19 tally to 1,17,34,058, the Union health ministry said on Wednesday. The active caseload registered an increase for the 14th day in a row and was recorded at 3,68,457, comprising 3.14 per cent of the total infections, while the recovery rate further dropped to 95.49 per cent, the ministry data updated at 8 am said.

The daily rise in infections was the highest recorded in 132 days, while the country's COVID-19 death toll increased to 1,60,441, with 275 new fatalities, the highest in around 83 days. As many as 47,905 new infections were recorded in a span of 24 hours on November 12 last year, it said. The number of people who have recuperated from the disease surged to 1,12,05,160, while the case fatality rate stands at 1.37 percent, the data stated.

Meanwhile, the number of COVID-19 vaccine doses administered in the country has crossed 5 crore, a significant milestone in the fight against the pandemic.

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