HomeNewsIndiaCOVID-19 pandemic | Districts in MP, Bihar, Telangana most vulnerable: Lancet study

COVID-19 pandemic | Districts in MP, Bihar, Telangana most vulnerable: Lancet study

According to scientists, including Rajib Acharya from the Population Council, New Delhi, vulnerability in the research means the risk of consequences of infection, including spread, morbidity, mortality, and social and economic effects of the pandemic.

July 17, 2020 / 13:10 IST
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Representative image: Reuters
Representative image: Reuters

While assessing several key indicators like housing, hygiene, and the health system in Madhya Pradesh, Bihar and Telangana, The Lancet Journal said that these states may be the most vulnerable to the effects of the COVID-19 pandemic.

According to scientists, including Rajib Acharya from the Population Council, New Delhi, vulnerability in the research means the risk of consequences of infection, including spread, morbidity, mortality, and social and economic effects of the pandemic.

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The study noted that nine of 30 large states -- Madhya Pradesh, Bihar and Telangana, Jharkhand, Uttar Pradesh, Maharashtra, West Bengal, Odisha, and Gujarat -- have high vulnerability to be impacted by the COVID-19 pandemic.

It rated the vulnerabilities of the states to the pandemic on a scale from zero to one, measured using 15 indicators across five domains -- socioeconomic, demographic, housing and hygiene, epidemiological, and health system.

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How does a vaccine work?

A vaccine works by mimicking a natural infection. A vaccine not only induces immune response to protect people from any future COVID-19 infection, but also helps quickly build herd immunity to put an end to the pandemic. Herd immunity occurs when a sufficient percentage of a population becomes immune to a disease, making the spread of disease from person to person unlikely. The good news is that SARS-CoV-2 virus has been fairly stable, which increases the viability of a vaccine.

How many types of vaccines are there?

There are broadly four types of vaccine — one, a vaccine based on the whole virus (this could be either inactivated, or an attenuated [weakened] virus vaccine); two, a non-replicating viral vector vaccine that uses a benign virus as vector that carries the antigen of SARS-CoV; three, nucleic-acid vaccines that have genetic material like DNA and RNA of antigens like spike protein given to a person, helping human cells decode genetic material and produce the vaccine; and four, protein subunit vaccine wherein the recombinant proteins of SARS-COV-2 along with an adjuvant (booster) is given as a vaccine.

What does it take to develop a vaccine of this kind?

Vaccine development is a long, complex process. Unlike drugs that are given to people with a diseased, vaccines are given to healthy people and also vulnerable sections such as children, pregnant women and the elderly. So rigorous tests are compulsory. History says that the fastest time it took to develop a vaccine is five years, but it usually takes double or sometimes triple that time.
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