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Pfizer requirements causing delays in COVAX deliveries: GAVI

Seth Berkley, CEO of the GAVI alliance that co-leads the COVAX multilateral vaccine facility with the World Health Organization (WHO), told journalists the requirements were partly related to indemnification issues.

March 02, 2021 / 19:51 IST
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The head of the GAVI vaccine alliance said on Tuesday that there have been delays to some Pfizer BioNTech COVID-19 shot deliveries via the COVAX vaccine-sharing programme because of additional requirements set by the manufacturer.

Seth Berkley, CEO of the GAVI alliance that co-leads the COVAX multilateral vaccine facility with the World Health Organization (WHO), told journalists the requirements were partly related to indemnification issues.

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At the same briefing, WHO adviser Bruce Aylward said it was still possible for COVID-19 vaccine rollouts to all participating countries to begin in the first 100 days of 2021 assuming that manufacturers can keep up with orders.

Follow our full coverage of the coronavirus pandemic here.

COVID-19 Vaccine
Frequently Asked Questions

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How does a vaccine work?

A vaccine works by mimicking a natural infection. A vaccine not only induces immune response to protect people from any future COVID-19 infection, but also helps quickly build herd immunity to put an end to the pandemic. Herd immunity occurs when a sufficient percentage of a population becomes immune to a disease, making the spread of disease from person to person unlikely. The good news is that SARS-CoV-2 virus has been fairly stable, which increases the viability of a vaccine.

How many types of vaccines are there?

There are broadly four types of vaccine — one, a vaccine based on the whole virus (this could be either inactivated, or an attenuated [weakened] virus vaccine); two, a non-replicating viral vector vaccine that uses a benign virus as vector that carries the antigen of SARS-CoV; three, nucleic-acid vaccines that have genetic material like DNA and RNA of antigens like spike protein given to a person, helping human cells decode genetic material and produce the vaccine; and four, protein subunit vaccine wherein the recombinant proteins of SARS-COV-2 along with an adjuvant (booster) is given as a vaccine.

What does it take to develop a vaccine of this kind?

Vaccine development is a long, complex process. Unlike drugs that are given to people with a diseased, vaccines are given to healthy people and also vulnerable sections such as children, pregnant women and the elderly. So rigorous tests are compulsory. History says that the fastest time it took to develop a vaccine is five years, but it usually takes double or sometimes triple that time.
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