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Exclusive: Poonawalla family's Serum Institute looks to raise $1 billion for big-ticket COVID-19 vaccine project

Investment banks Goldman Sachs, Citi and Avendus Capital have been engaged as advisors for the process by the privately held vaccine manufacturer, say sources.

June 26, 2020 / 23:46 IST
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Pune-headquartered Serum Institute of India, the world’s largest vaccine manufacturer and a frontrunner in India’s fight against COVID-19, plans to raise around $1 billion as it looks to mass-produce billions of doses of COVID-19 experimental vaccines on the back of tie-ups with various global firms, sources with knowledge of the matter told Moneycontrol. One of these arrangements includes a critical licence to mass-produce an experimental COVID -19 vaccine by University of Oxford and British drugmaker AstraZeneca, which has entered the final stage of clinical trials.

“This is a big project of national importance and Serum, a national vaccine champion, is trying to address a global pandemic. They are looking to rope in suitable investors/partners to fund this novel project and raise nearly billion dollars in lieu of a minority stake in the company,” said one of the individuals cited above.

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Investment banks Goldman Sachs, Citi and Avendus Capital have been engaged as advisors for the process by the privately held Serum Institute, he added, saying the deal is at a preliminary stage and may or may not necessarily result in a transaction.

“R&D, especially for a project of this nature, is expensive along with investments in manufacturing plants and emerging technologies. There is a development risk attached as well. So it’s a prudent strategy to get in partners with the right background and capabilities,” said a second person.

COVID-19 Vaccine
Frequently Asked Questions

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How does a vaccine work?

A vaccine works by mimicking a natural infection. A vaccine not only induces immune response to protect people from any future COVID-19 infection, but also helps quickly build herd immunity to put an end to the pandemic. Herd immunity occurs when a sufficient percentage of a population becomes immune to a disease, making the spread of disease from person to person unlikely. The good news is that SARS-CoV-2 virus has been fairly stable, which increases the viability of a vaccine.

How many types of vaccines are there?

There are broadly four types of vaccine — one, a vaccine based on the whole virus (this could be either inactivated, or an attenuated [weakened] virus vaccine); two, a non-replicating viral vector vaccine that uses a benign virus as vector that carries the antigen of SARS-CoV; three, nucleic-acid vaccines that have genetic material like DNA and RNA of antigens like spike protein given to a person, helping human cells decode genetic material and produce the vaccine; and four, protein subunit vaccine wherein the recombinant proteins of SARS-COV-2 along with an adjuvant (booster) is given as a vaccine.

What does it take to develop a vaccine of this kind?

Vaccine development is a long, complex process. Unlike drugs that are given to people with a diseased, vaccines are given to healthy people and also vulnerable sections such as children, pregnant women and the elderly. So rigorous tests are compulsory. History says that the fastest time it took to develop a vaccine is five years, but it usually takes double or sometimes triple that time.
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