In a finding that could turn the tables on modern stroke treatment, researchers have discovered that a powerful hallucinogenic compound found in the brain, Dimethyltryptamine (DMT), may actually help it heal. Long associated with psychedelic experiences, DMT is now being eyed as a serious player in the field of neurology. And while it may sound like science fiction, the hard science is in: when it comes to repairing brain damage after a stroke, this mind-bending molecule is showing serious promise.
What the study says: From psychedelia to prescription pad
In what reads like the plot of a far-out sci-fi film, Hungarian researchers from the HUN-REN Szegedi Biológiai Kutatóközpont and Semmelweis University have revealed that DMT, or dimethyltryptamine, can dramatically reduce the effects of stroke, at least in rats and cell cultures, for now.
Also read | Stroke symptoms and warning signs: Remember, the 'golden window' to treat a stoke is just 4.5 hours
Their findings, published in Science Advances, show that DMT not only shrinks the size of brain damage caused by stroke but also restores crucial brain functions by mending the blood-brain barrier.
According to co-lead author Mária Deli, “It is amazing how we can always turn to nature to find ingenious solutions for health problems.” And indeed, DMT, a substance naturally produced in the human brain, may soon become part of the neurologist’s resources.
What is the ‘spirit molecule’
- Protects the blood-brain barrier: Stroke often damages this vital defence system. DMT helps restore its structure and function.
- Reduces swelling in the brain: DMT was shown to reduce both infarct volume (damaged brain area) and brain swelling in rat models.
- Fights inflammation: The compound decreases inflammatory signals and calms immune cells in the brain and body.
- Targets Sigma-1 receptors: These receptors, key to cellular stress responses, are activated by DMT to aid healing.
- Supports glial cell function: Astroglial cells, the brain’s support staff, bounced back under DMT’s influence.
Modern stroke treatments are limited, and often don’t lead to full recovery. This is where DMT could help. According to co-author Judit Vigh, DMT’s dual role, reducing inflammation and protecting the blood-brain barrier, could work alongside current therapies to improve patient outcomes.
Clinical trials are already underway, and while much remains to be studied, the buzz is building. What was once dismissed as a hippy hallucination might now be the brain’s best shot at bouncing back after a stroke.
FAQs on Stroke Symptoms
1. What are common stroke symptoms?
Common stroke symptoms include sudden numbness or weakness in the face, arm, or leg, especially on one side of the body; confusion; trouble speaking or understanding speech; vision problems; difficulty walking; dizziness; and severe headache.
2. What should you do if you suspect someone is having a stroke?
If you suspect someone is having a stroke, call emergency services immediately. Quick medical attention is crucial as the "golden window" for effective treatment is within 4.5 hours of symptom onset.
3. Can stroke symptoms be temporary?
Yes, stroke symptoms can be temporary, especially in the case of a transient ischemic attack (TIA), which is often a warning sign of a potential future stroke and requires immediate medical attention.
4. How does DMT help in stroke recovery?
DMT helps in stroke recovery by reducing brain damage size, restoring brain functions, protecting the blood-brain barrier, reducing swelling, fighting inflammation, and supporting glial cell function.
5. Is DMT being used in current stroke treatments?
While DMT shows promise in preclinical studies for stroke treatment, it is not yet a standard therapy. Ongoing clinical trials aim to determine its efficacy and safety for future use in stroke recovery.
Disclaimer: This article, including health and fitness advice, only provides generic information. Don’t treat it as a substitute for qualified medical opinion. Always consult a specialist for a specific health diagnosis.
Discover the latest Business News, Sensex, and Nifty updates. Obtain Personal Finance insights, tax queries, and expert opinions on Moneycontrol or download the Moneycontrol App to stay updated!
