HomeNewsIndiaCOVID-19 vaccine for children | Clinical trials may begin in India by mid-2021: Report

COVID-19 vaccine for children | Clinical trials may begin in India by mid-2021: Report

The Pfizer vaccine authorised in the United Kingdom and the United States is for people of age 16 years and older.

December 22, 2020 / 10:13 IST
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A child wearing a protection mask and gloves is seen at Indira Gandhi International (IGI) airport. (Image: Reuters)
A child wearing a protection mask and gloves is seen at Indira Gandhi International (IGI) airport. (Image: Reuters)

Amid the growing COVID-19 cases and emerging new coronavirus strain, the vaccine against COVID-19 promises a return to normal in the not-so-distant future. For people aged 16 years and above, the vaccine shot has been developed.

While the elderly are a high-risk group and on the list of people to receive the COVID-19 vaccine after health care workers and frontline staff, what about the youngest members of society – children? Vaccine manufacturers in the race to develop the vaccine against the contagion believe that progress on paediatric versions is not far behind, Business Standard reported quoting sources.

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“Once the immunisation programme starts and one can observe the vaccines in use on a mass-scale, the safety of these investigational products would be established beyond doubt. It is around the middle of the next year that one would plan to start clinical trials for children,” a leading vaccine maker, which is in the final leg of developing a COVID-19 vaccine, told the publication.

The Pfizer vaccine authorised in the United Kingdom and the United States is for people of age 16 years and older. Also, testing began in October in children as young as 12 and is expected to take several more months.

COVID-19 Vaccine
Frequently Asked Questions

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How does a vaccine work?

A vaccine works by mimicking a natural infection. A vaccine not only induces immune response to protect people from any future COVID-19 infection, but also helps quickly build herd immunity to put an end to the pandemic. Herd immunity occurs when a sufficient percentage of a population becomes immune to a disease, making the spread of disease from person to person unlikely. The good news is that SARS-CoV-2 virus has been fairly stable, which increases the viability of a vaccine.

How many types of vaccines are there?

There are broadly four types of vaccine — one, a vaccine based on the whole virus (this could be either inactivated, or an attenuated [weakened] virus vaccine); two, a non-replicating viral vector vaccine that uses a benign virus as vector that carries the antigen of SARS-CoV; three, nucleic-acid vaccines that have genetic material like DNA and RNA of antigens like spike protein given to a person, helping human cells decode genetic material and produce the vaccine; and four, protein subunit vaccine wherein the recombinant proteins of SARS-COV-2 along with an adjuvant (booster) is given as a vaccine.

What does it take to develop a vaccine of this kind?

Vaccine development is a long, complex process. Unlike drugs that are given to people with a diseased, vaccines are given to healthy people and also vulnerable sections such as children, pregnant women and the elderly. So rigorous tests are compulsory. History says that the fastest time it took to develop a vaccine is five years, but it usually takes double or sometimes triple that time.
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