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The second virus wave: How bad will it be as lockdowns ease?

A century ago, the Spanish flu epidemic’s second wave was far deadlier than its first, in part because authorities allowed mass gatherings from Philadelphia to San Francisco.

May 06, 2020 / 21:43 IST
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From the marbled halls of Italy to the wheat fields of Kansas, health authorities are increasingly warning that the question isn’t whether a second wave of coronavirus infections and deaths will hit, but when — and how badly.

In India, which relaxed its lockdown this week, health authorities scrambled Wednesday to contain an outbreak at a huge market. Hard-hit New York City shut down its subway system overnight for disinfection. Experts in Italy, which just began easing some restrictions, warned lawmakers that a new surge of infections and deaths is coming, and they urged intensified efforts to identify victims, monitor their symptoms and trace their contacts.

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German Chancellor Angela Merkel said after meeting with the country’s 16 governors that restaurants and remaining shops will be allowed to reopen in the coming weeks but that restrictions will be reimposed if new infections hit a certain level.

“There will be a second wave, but the problem is to which extent. Is it a small wave or a big wave? It’s too early to say,” said Olivier Schwartz, head of the virus and immunity unit at France’s Pasteur Institute. France, which hasn't yet eased its lockdown, has worked up a “re-confinement plan” to ready for that second wave.

COVID-19 Vaccine
Frequently Asked Questions

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How does a vaccine work?

A vaccine works by mimicking a natural infection. A vaccine not only induces immune response to protect people from any future COVID-19 infection, but also helps quickly build herd immunity to put an end to the pandemic. Herd immunity occurs when a sufficient percentage of a population becomes immune to a disease, making the spread of disease from person to person unlikely. The good news is that SARS-CoV-2 virus has been fairly stable, which increases the viability of a vaccine.

How many types of vaccines are there?

There are broadly four types of vaccine — one, a vaccine based on the whole virus (this could be either inactivated, or an attenuated [weakened] virus vaccine); two, a non-replicating viral vector vaccine that uses a benign virus as vector that carries the antigen of SARS-CoV; three, nucleic-acid vaccines that have genetic material like DNA and RNA of antigens like spike protein given to a person, helping human cells decode genetic material and produce the vaccine; and four, protein subunit vaccine wherein the recombinant proteins of SARS-COV-2 along with an adjuvant (booster) is given as a vaccine.

What does it take to develop a vaccine of this kind?

Vaccine development is a long, complex process. Unlike drugs that are given to people with a diseased, vaccines are given to healthy people and also vulnerable sections such as children, pregnant women and the elderly. So rigorous tests are compulsory. History says that the fastest time it took to develop a vaccine is five years, but it usually takes double or sometimes triple that time.
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