HomeNewsTrendsHealthH5N1 bird flu: What experts say about the disease that could be '100 times worse than Covid-19'
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H5N1 bird flu: What experts say about the disease that could be '100 times worse than Covid-19'

This marks the first case of the highly pathogenic strain of bird flu infecting cattle

April 05, 2024 / 18:44 IST
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The Centers for Disease Control and Prevention (CDCP) has confirmed at least one human case of avian influenza infection in Texas linked to contact with an infected cattle
The Centers for Disease Control and Prevention (CDCP) has confirmed at least one human case of avian influenza infection in Texas linked to contact with an infected cattle

An outbreak of bird flu has now spread to dairy cattle herds across six states in the US. This marks the first case of the highly pathogenic strain of bird flu infecting cattle. An expert cited by UK’s Dailymail tabloid warned that the HN51 outbreak could be “100 times worse than” Covid.

“And now we are getting dangerously close to this virus potentially causing a pandemic,” Dr Suresh Kuchipudi, a bird flu researcher in Pittsburgh, said at a briefing.

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Backing Kuchipudi’s concerns, John Fulton, a pharmaceutical industry consultant for vaccines and founder of Canada-based company BioNiagara, said, “I think this is a virus that has the greatest pandemic threat [that is] playing out in plain sight and is globally present. This appears to be 100 times worse than Covid, or it could be if it mutates and maintains its high case fatality rate.”

The Centers for Disease Control and Prevention (CDCP) has confirmed at least one human case of avian influenza infection in Texas linked to contact with an infected cattle. The individual, exhibiting conjunctivitis as the primary symptom, has been treated with antivirals and is reported to be recovering.

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How does a vaccine work?

A vaccine works by mimicking a natural infection. A vaccine not only induces immune response to protect people from any future COVID-19 infection, but also helps quickly build herd immunity to put an end to the pandemic. Herd immunity occurs when a sufficient percentage of a population becomes immune to a disease, making the spread of disease from person to person unlikely. The good news is that SARS-CoV-2 virus has been fairly stable, which increases the viability of a vaccine.

How many types of vaccines are there?

There are broadly four types of vaccine — one, a vaccine based on the whole virus (this could be either inactivated, or an attenuated [weakened] virus vaccine); two, a non-replicating viral vector vaccine that uses a benign virus as vector that carries the antigen of SARS-CoV; three, nucleic-acid vaccines that have genetic material like DNA and RNA of antigens like spike protein given to a person, helping human cells decode genetic material and produce the vaccine; and four, protein subunit vaccine wherein the recombinant proteins of SARS-COV-2 along with an adjuvant (booster) is given as a vaccine.

What does it take to develop a vaccine of this kind?

Vaccine development is a long, complex process. Unlike drugs that are given to people with a diseased, vaccines are given to healthy people and also vulnerable sections such as children, pregnant women and the elderly. So rigorous tests are compulsory. History says that the fastest time it took to develop a vaccine is five years, but it usually takes double or sometimes triple that time.
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