HomeNewsHealth & FitnessCan diabetes lead to vascular disease? How to prevent vascular complications in diabetes

Can diabetes lead to vascular disease? How to prevent vascular complications in diabetes

Diabetes is a chronic condition, but it doesn't have to control your life. Follow these steps to significantly control your blood sugar levels, reduce your risk of vascular complications, and live a longer, healthier life.

December 24, 2023 / 20:25 IST
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People with diabetes are at higher risk of developing atherosclerosis, the most common cause of peripheral artery disease, which is a kind of vascular disease. (Photo: X)
People with diabetes are at higher risk of developing atherosclerosis, the most common cause of peripheral artery disease, which is a kind of vascular disease. (Photo: X)

The World Health Organisation states that a person is diagnosed with diabetes when the fasting blood sugar levels are more than 125 mg/dL on two separate tests or HbA1c of 6.5 per cent or more or random blood sugar levels of 200 mg/dL. The condition revolves around the hormone insulin that regulates glucose metabolism. When the body either doesn’t make enough insulin, (type 1 diabetes) or can’t utilise it properly (type 2 diabetes), too much glucose or sugar flows in the bloodstream.

Over time, this is essentially what happens to your blood vessels when you have diabetes:

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1.    Production of harmful sticky molecules: Excess glucose molecules combine with proteins and fats in the blood to make harmful molecules called Advanced Glycation End products (AGEs). These AGEs stick to the inner lining of your blood vessels, making them relatively stiffer, less flexible, and more prone to damage.

2.    Swelling/inflammation: Chronically high blood sugar levels trigger inflammation throughout the body. This inflammation weakens the blood vessels and contributes to the buildup of plaque, a fatty substance that sticks to the walls of the arteries.