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How ‘El Señor Mencho’ rose to the top: America’s cocaine comeback and Mexico’s new cartel order

The Trump administration’s fentanyl crackdown reshaped the drug market — boosting cocaine demand and elevating Jalisco’s Nemesio “Mencho” Oseguera

September 17, 2025 / 14:05 IST
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How ‘El Señor Mencho’ rose to the top: America’s cocaine comeback and Mexico’s new cartel order

As Washington intensified efforts to curb fentanyl, the Sinaloa cartel — long the dominant synthetic-opioid trafficker — came under heavy pressure. That spotlight, combined with infighting inside Sinaloa, opened space for the Jalisco New Generation Cartel (CJNG) to scale a more traditional business: cocaine. With prices falling and purity steady for US buyers, consumption rose, especially in the West, positioning CJNG to capitalize, the Wall Street Journal reported.

The ascent of ‘Mencho’ and CJNG

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From a fortified base in the Sierra Madre, 59-year-old Oseguera consolidated CJNG into a transnational organization capable of challenging and displacing Sinaloa’s fractured network. US officials now describe him as the most powerful trafficker globally. CJNG’s logistics push multi-ton cocaine loads from Colombia via Ecuador up the Pacific — using speedboats and semi-submersible “narco subs” — into Mexico, then across the US border.

Market signals: cocaine up, fentanyl down