HomeHealth & FitnessIs ‘man-flu’ real? What science says about how men and women experience illness differently

Is ‘man-flu’ real? What science says about how men and women experience illness differently

Is ‘man-flu’ real or just a joke? Know whether men truly experience colds and flu more severely — and what science says about gender and immunity.

October 16, 2025 / 14:01 IST
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Man-flu explained: Why men may experience flu symptoms differently from women (Image: Pexels)
Man-flu explained: Why men may experience flu symptoms differently from women (Image: Pexels)

You must have heard the joke - men get "man-flu", a simple cold or flu that they dramatize and make into the biggest problem in their world and for people around them. It is a tongue-in-cheek label used to mock men who act to suffer more even from a common flu. But is it just a cultural stereotype, or is there some reality behind it?

In a recent Instagram video, a lifestyle and health creator, Doctor Myro, shows a man dramatically acting as though he is dying from a mild flu while the woman is casually going through her day. The clip shows the trope that men are perceived to overstate their symptoms, whereas women just go through the day like it's nothing. The video raises an important question: whether man-flu is just psychological or it has some biological merit to it?

What Does Science Say?

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In the video, Doctor Myro shares that research indicates sex hormones influence immune function. Testosterone, progesterone, and estrogen all affect how the immune system reacts to infection.

According to some research, women may have more effective viral clearance because they develop stronger innate and adaptive immune responses to specific viruses.