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During fasting, insulin levels fall while glucose rises, promoting liver glycogen breakdown, and glucose release
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Short‑term fasting has been shown to improve insulin sensitivity and reduce insulin resistance in type 2 diabetics.
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Some intermittent fasting trials record lower HbA₁c levels and fasting glucose in diabetic subjects over months.
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Fasting often contributes to weight loss, which in turn helps reduce insulin resistance and improve metabolic health
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The metabolic benefits of fasting seen in short term tend to diminish or align with control diets after longer time periods.
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In type 1 diabetics or those on insulin/secretagogues, fasting heightens the danger of low blood sugar episodes without careful adjustment.
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Fasting or restricted eating may reduce inflammatory biomarkers like CRP, which is linked to insulin resistance.
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Chronic stress and cortisol surges can blunt fasting benefits by raising blood glucose even when you’re not eating.
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A sudden glucose intake after prolonged fast in diabetic patients can provoke oxidative stress and metabolic stress.
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Responses to fasting vary, age, medications, insulin dosage, disease stage all require a tailored plan under medical supervision.