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Liver cirrhosis is the end-stage of any type of longstanding liver disease. The liver may be covered either by small nodules or large nodules
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It is characterised by formation of fibrous tissue in the liver along with a loss of the normal architecture of the liver parenchyma
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One of the most common causes of liver cirrhosis is long term alcohol consumption. Alongside, hepatitis B and C can also lead to this disease
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Certain drugs like methotrexate (used in rheumatoid arthritis), methyldopa (used in hypertension) and isoniazid can also lead to cirrhosis
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General, non-specific symptoms include weakness, weight loss, anorexia, nausea and vomiting, and abdominal pain
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In women, loss of hair, irregular menstruation and absence of menstruation may be seen in case of liver cirrhosis
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Men may show gynecomastia (enlargement of breast tissue in males), testicular atrophy and impotence due to cirrhosis
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The liver physiologically produces coagulation factors. In cirrhosis, the reduced production can cause easy bruising and bleeding from the nose
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Flapping tremors, also known as asterixis, may also be noted when the arms are stretched with the fingers facing upwards
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While there is no way to reverse it, liver transplantation can be tried. Cessation of alcohol consumption is necessary to avoid progression of the condition