9 main culprits of infertility: From lifestyle to genetics

9 main culprits of infertility: From lifestyle to genetics

By Saumya Rastogi | March 26, 2025 | Images: Freepik

Hormonal imbalances

Disruptions in reproductive hormones (like estrogen, progesterone, and testosterone) can affect ovulation in women and sperm production in men

Poor diet and obesity

Excess weight leads to hormonal imbalances, affecting ovulation in women and reducing sperm count in men. A diet high in processed foods, trans fats, and sugar negatively impacts reproductive health

Smoking, alcohol and drug use

Cigarettes and alcohol damage egg and sperm quality, reduce fertility rates, and increase the risk of miscarriage. Recreational drugs like marijuana and anabolic steroids can further disrupt hormone levels

Stress and sleep deprivation

Chronic stress increases cortisol levels, which can suppress reproductive hormones, leading to irregular ovulation in women and lower sperm production in men. Lack of sleep further disrupts hormonal balance

Environmental toxins and pollution

Exposure to pesticides, heavy metals, endocrine-disrupting chemicals (like BPA in plastics), and air pollution can lower fertility in both men and women by damaging eggs and sperm

Age and delayed parenthood

Fertility declines with age, especially in women after 35, as egg quality and quantity decrease. In men, sperm quality also deteriorates over time, leading to increased risks of infertility

Medical conditions and genetic disorders

Conditions such as endometriosis, fibroids, blocked fallopian tubes, and autoimmune diseases can affect female fertility. In men, varicocele (swollen testicular veins) and genetic disorders like Klinefelter syndrome can reduce sperm production

Sexually transmitted infections (STIs)

Untreated STIs like chlamydia and gonorrhea can cause pelvic inflammatory disease (PID) in women, leading to blocked fallopian tubes. In men, infections can lead to sperm damage or blockages in sperm transport

Excessive exercise or lack of physical activity

Extreme workouts can disrupt menstrual cycles and lower sperm count due to excess stress on the body. Conversely, a sedentary lifestyle contributes to obesity and poor reproductive health

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