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New coronavirus variant does not cause illness more severe than others: Study

Scientists say the new variant can spread more rapidly. It was found in England in mid December and led to other countries imposing travel restrictions to the United Kingdom. Several other countries have reported variants.

December 30, 2020 / 08:45 AM IST
Germany | Germans enjoyed a largely relaxed summer with many restrictions lifted, the dividend of a rapid response to the initial coronavirus outbreak and a reliance on early and widespread testing that won wide praise. It brought the number of daily COVID-19 cases down from a peak of more than 6,000 in late March to the few hundreds by the warmer months. But as people grew lax in following the rules the numbers began to climb to nearly quadruple the March daily record, and the country now finds itself in a new lockdown as it tries to bring the pandemic back under control. (Image: AP)

Germany | Germans enjoyed a largely relaxed summer with many restrictions lifted, the dividend of a rapid response to the initial coronavirus outbreak and a reliance on early and widespread testing that won wide praise. It brought the number of daily COVID-19 cases down from a peak of more than 6,000 in late March to the few hundreds by the warmer months. But as people grew lax in following the rules the numbers began to climb to nearly quadruple the March daily record, and the country now finds itself in a new lockdown as it tries to bring the pandemic back under control. (Image: AP)

A new variant of the novel coronavirus does not appear to cause more severe illness than other variants, according to a matched study by Public Health England.

Scientists say the new variant can spread more rapidly. It was found in England in mid December and led to other countries imposing travel restrictions to the United Kingdom. Several other countries have reported variants.

Under the study, researchers compared 1,769 people infected with the new variant with 1,769 who had what they described as "wild-type" virus. The two groups were matched 1:1 on the basis of age, sex, area of residence and time of testing.

Of the 42 people who were admitted to hospital, 16 were infected with the new variant while 26 cases had wild type infection, according to the study. In terms of fatality, there were 12 deaths in variant cases compared to 10 deaths in wild-type cases.

"Preliminary results from the cohort study found no statistically significant difference in hospitalisation and 28-day case fatality between cases with the variant and wild-type comparator cases," the study said.

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COVID-19 Vaccine

Frequently Asked Questions

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How does a vaccine work?

A vaccine works by mimicking a natural infection. A vaccine not only induces immune response to protect people from any future COVID-19 infection, but also helps quickly build herd immunity to put an end to the pandemic. Herd immunity occurs when a sufficient percentage of a population becomes immune to a disease, making the spread of disease from person to person unlikely. The good news is that SARS-CoV-2 virus has been fairly stable, which increases the viability of a vaccine.

How many types of vaccines are there?

There are broadly four types of vaccine — one, a vaccine based on the whole virus (this could be either inactivated, or an attenuated [weakened] virus vaccine); two, a non-replicating viral vector vaccine that uses a benign virus as vector that carries the antigen of SARS-CoV; three, nucleic-acid vaccines that have genetic material like DNA and RNA of antigens like spike protein given to a person, helping human cells decode genetic material and produce the vaccine; and four, protein subunit vaccine wherein the recombinant proteins of SARS-COV-2 along with an adjuvant (booster) is given as a vaccine.

What does it take to develop a vaccine of this kind?

Vaccine development is a long, complex process. Unlike drugs that are given to people with a diseased, vaccines are given to healthy people and also vulnerable sections such as children, pregnant women and the elderly. So rigorous tests are compulsory. History says that the fastest time it took to develop a vaccine is five years, but it usually takes double or sometimes triple that time.

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There was no significant difference in the likelihood of reinfection with the new variant as compared with the other variants, it said.

The study, however, added that the "secondary attack rate", or the proportion of contacts of confirmed cases that develop disease themselves, was higher in people infected with the new variant.

Earlier on Tuesday a leading epidemiologist who advises the government, Andrew Hayward, warned that Britain was heading for "catastrophe" over the coming weeks if it did not take tougher action against the more infectious variant of the disease.

Britain reported 53,135 new cases of COVID-19 on Tuesday, the highest number since mass testing started in mid-2020. British Prime Minister Boris Johnson has approved placing more parts of the country into the highest level of restrictions, known as tier 4, The Times reported.
Reuters
first published: Dec 30, 2020 08:38 am

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