Moneycontrol PRO
Upcoming Webinar:Join us for 'The Future Techshot' on Sept 22, 10:30am to gain insights into role of tech in streamlining businesses. Register Now!
you are here: HomeNewsWorld

Combining AstraZeneca and mRNA COVID-19 vaccines is effective -Danish study

More than 144,000 Danes, mostly frontline personnel in the health sector and the elderly, received their first jab with AstraZeneca's vaccine but were subsequently vaccinated with either Pfizer-BioNTech or Moderna's shots.

August 02, 2021 / 09:04 PM IST

Combining AstraZeneca's COVID-19 vaccine with a second dose from either Pfizer-BioNTech or Moderna's jab provides "good protection", Denmark's State Serum Institute said on Monday.

A growing number of countries are looking at switching to different COVID-19 vaccines for second doses, a measure particularly necessary in Denmark after health authorities discontinued inoculations with AstraZeneca's vaccine in April over rare side-effect concerns.

More than 144,000 Danes, mostly frontline personnel in the health sector and the elderly, received their first jab with AstraZeneca's vaccine but were subsequently vaccinated with either Pfizer-BioNTech or Moderna's shots.

"The study shows that fourteen days after a combined vaccination program, the risk of infection with SARS-CoV-2 is reduced by 88% compared to unvaccinated individuals," the State Serum Institute (SSI) said.

That is a "high efficacy", SSI added, comparable to the 90% efficacy rate of two doses from Pfizer-BioNTech's vaccine, confirmed in a different Danish study.

Close

COVID-19 Vaccine

Frequently Asked Questions

View more
How does a vaccine work?

A vaccine works by mimicking a natural infection. A vaccine not only induces immune response to protect people from any future COVID-19 infection, but also helps quickly build herd immunity to put an end to the pandemic. Herd immunity occurs when a sufficient percentage of a population becomes immune to a disease, making the spread of disease from person to person unlikely. The good news is that SARS-CoV-2 virus has been fairly stable, which increases the viability of a vaccine.

How many types of vaccines are there?

There are broadly four types of vaccine — one, a vaccine based on the whole virus (this could be either inactivated, or an attenuated [weakened] virus vaccine); two, a non-replicating viral vector vaccine that uses a benign virus as vector that carries the antigen of SARS-CoV; three, nucleic-acid vaccines that have genetic material like DNA and RNA of antigens like spike protein given to a person, helping human cells decode genetic material and produce the vaccine; and four, protein subunit vaccine wherein the recombinant proteins of SARS-COV-2 along with an adjuvant (booster) is given as a vaccine.

What does it take to develop a vaccine of this kind?

Vaccine development is a long, complex process. Unlike drugs that are given to people with a diseased, vaccines are given to healthy people and also vulnerable sections such as children, pregnant women and the elderly. So rigorous tests are compulsory. History says that the fastest time it took to develop a vaccine is five years, but it usually takes double or sometimes triple that time.

View more
Show

The study, published last week, covered a span of more than five months between February and June this year, a period in which the Alpha-variant of the coronavirus was predominant.

It could not conclude whether the same protection applied to the Delta-variant, which is now the most widespread in Denmark.

It also provided no efficacy data on COVID-19 related deaths or hospitalisations, since none took place following the combined vaccination programme.

 
Reuters
first published: Aug 2, 2021 09:04 pm

stay updated

Get Daily News on your Browser
Sections
ISO 27001 - BSI Assurance Mark