HomeNewsTrendsHealthDoctors in China, India wrote about isolation over 2,000 years ago: Peter Frankopan

Doctors in China, India wrote about isolation over 2,000 years ago: Peter Frankopan

Peter Frankopan's 2015 book The Silk Roads: A New History of the World sold 1.5 million copies worldwide and was named among the 'Books of the Decade' by the Sunday Times, London.

April 16, 2020 / 11:01 IST
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Called a 'rock star historian', Peter Frankopan is a professor of global history at the Oxford University. His 2015 book The Silk Roads: A New History of the World sold 1.5 million copies worldwide and was named among the 'Books of the Decade' by the Sunday Times, London. The follow-up book The New Silk Roads: The Future and Present of the World, about a new world forming across the spine of Asia, linking China, Russia, Iran, the Middle East with Central and South Asia published in 2018, is a major international bestseller.

A Fellow of the Royal Historical Society and the Royal Asiatic Society, Prof. Frankopan, one of the speakers of Jaipur Literature Festival's ongoing 'Brave New World' digital literature series, talks to Faizal Khan about the history of pandemics and how the coronavirus outbreak will define the future of the world.

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Q: You have argued in your works that diseases had spread across the world in the past just like languages and cultures. How can history help us understand a pandemic?

A: Pandemics have occurred many times in the past. Doctors in China and India were writing about the importance of isolation more than two thousand years ago. So we can use history in three ways: first, we can take comfort that our ancestors have had to deal with these things before, and in doing so, get some perspective not only on what they lived through but also what we are dealing with today as well. However awful the current situation, it is better than the plague outbreak in Mumbai in 1896, when the city was also being ravaged by cholera, tuberculosis and other diseases.

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A vaccine works by mimicking a natural infection. A vaccine not only induces immune response to protect people from any future COVID-19 infection, but also helps quickly build herd immunity to put an end to the pandemic. Herd immunity occurs when a sufficient percentage of a population becomes immune to a disease, making the spread of disease from person to person unlikely. The good news is that SARS-CoV-2 virus has been fairly stable, which increases the viability of a vaccine.

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There are broadly four types of vaccine — one, a vaccine based on the whole virus (this could be either inactivated, or an attenuated [weakened] virus vaccine); two, a non-replicating viral vector vaccine that uses a benign virus as vector that carries the antigen of SARS-CoV; three, nucleic-acid vaccines that have genetic material like DNA and RNA of antigens like spike protein given to a person, helping human cells decode genetic material and produce the vaccine; and four, protein subunit vaccine wherein the recombinant proteins of SARS-COV-2 along with an adjuvant (booster) is given as a vaccine.

What does it take to develop a vaccine of this kind?

Vaccine development is a long, complex process. Unlike drugs that are given to people with a diseased, vaccines are given to healthy people and also vulnerable sections such as children, pregnant women and the elderly. So rigorous tests are compulsory. History says that the fastest time it took to develop a vaccine is five years, but it usually takes double or sometimes triple that time.
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