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Coronavirus killed more people under 50 years than 65+ age group: AIIMS study

During the AIIMS study, a total of 654 adult COVID-19 patients were admitted to the ICU

June 29, 2021 / 10:00 AM IST
During the study, a total of 654 adult patients were admitted to the Intensive Care Unit (ICU). Of these, 247 died, showing a mortality rate of 37.7 percent (247 out of 654).

During the study, a total of 654 adult patients were admitted to the Intensive Care Unit (ICU). Of these, 247 died, showing a mortality rate of 37.7 percent (247 out of 654).

COVID-19 has claimed the lives of more people under the age of 50 than of those above 65 years, showed a new study conducted by the All India Institute of Medical Sciences (AIIMS), Delhi, reported news agency ANI.

The single-center retrospective study, authored by AIIMS director Dr Randeep Guleria, chief of the AIIMS trauma center Dr Rajesh Malhotra and several others, published in the Indian Journal of Critical Care Medicine. The assessment primarily dealt with the deaths of COVID-19 adult patients who were admitted between April 4 and July 24, 2020, reported news agency ANI.

The AIIMS study was conducted to describe the clinic epidemiological feature as well as find out the causes of mortality in patients admitted to dedicated COVID-19 centers in India, said the report.

During the study, a total of 654 adult patients were admitted to the Intensive Care Unit (ICU). Of these, 247 died, showing a mortality rate of 37.7 percent (247 out of 654).

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COVID-19 Vaccine

Frequently Asked Questions

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How does a vaccine work?

A vaccine works by mimicking a natural infection. A vaccine not only induces immune response to protect people from any future COVID-19 infection, but also helps quickly build herd immunity to put an end to the pandemic. Herd immunity occurs when a sufficient percentage of a population becomes immune to a disease, making the spread of disease from person to person unlikely. The good news is that SARS-CoV-2 virus has been fairly stable, which increases the viability of a vaccine.

How many types of vaccines are there?

There are broadly four types of vaccine — one, a vaccine based on the whole virus (this could be either inactivated, or an attenuated [weakened] virus vaccine); two, a non-replicating viral vector vaccine that uses a benign virus as vector that carries the antigen of SARS-CoV; three, nucleic-acid vaccines that have genetic material like DNA and RNA of antigens like spike protein given to a person, helping human cells decode genetic material and produce the vaccine; and four, protein subunit vaccine wherein the recombinant proteins of SARS-COV-2 along with an adjuvant (booster) is given as a vaccine.

What does it take to develop a vaccine of this kind?

Vaccine development is a long, complex process. Unlike drugs that are given to people with a diseased, vaccines are given to healthy people and also vulnerable sections such as children, pregnant women and the elderly. So rigorous tests are compulsory. History says that the fastest time it took to develop a vaccine is five years, but it usually takes double or sometimes triple that time.

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The adult patients were further divided into several age groups to compare their clinical characteristics and outcomes -- 18 to 50, 51 to 65, and above 65. The study result showed 42.1 percent of the deaths were among the age group 18-50 years, 34.8 percent in 51-65, and 23.1 percent among those above 65.

The most common aspects in most of these deceased COVID-19 patients include hypertension, diabetes mellitus, and chronic kidney diseases along with the most common presenting features being fever, cough, and shortness of breath.

This data of all the deceased patients were collected from their electronic medical report, patients' daily progress charts, as well as nursing notes in the ICU, said the report.

Also read | Third shot of the Oxford-AstraZeneca COVID-19 vaccine produces strong immune response: Study

The report further said that ICU mortality among COVID-19 patients varies between 8.0 percent and 66.7 percent in different studies. "In our center, however, the hospital mortality was 18.2 pc and ICU mortality was 36.1 percent," said the report citing the study.

Several other countries, such as the United States, Spain, and Italy have also reported similar mortality rates, it said.

The study further recorded the deaths of Pediatric admitted during the period. The data showed that out of 46 admitted pediatric patients, six died of novel coronavirus infection. With this, the ICU mortality among the Pediatric group was 13 percent, the study suggested.

Also read | COVID-19 Vaccine Tracker | 52.76 lakh doses administered in India on June 28

India has so far registered 3,97,637 deaths due to COVID-19 disease, according to the union health ministry’s data updated on June 29.

Follow our full coverage on COVID-19 here.



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first published: Jun 29, 2021 10:00 am
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