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Last Updated : Aug 04, 2020 11:05 AM IST | Source: Moneycontrol.com

Anand Mahindra's tweet on 'Big V' vaccine: Here's how Adar Poonawalla responded

In a tweet on August 2, Mahindra had joked about a vaccine called "Big V", a reference to the Amitabh Bachchan's popular nickname "Big B" and how all of India needs a dose of that.

Image: Twitter/ @adarpoonawalla
Image: Twitter/ @adarpoonawalla

As the world awaits a vaccine for Coronavirus, the chatter in India is increasing further and Anand Mahindra, keeping things light like he does, took the conversation ahead in his own signature way.

On August 2, Industrialist Anand Mahindra had welcomed actor Amitabh Bachchan after his recovery from COVID-19.

In a tweet, Mahindra joked about a vaccine called "Big V", a reference to the actor's popular nickname "Big B" and how all of India needs a dose of that.


Mahindra said, "Now we need Adar Poonawalla to find a way to extract it from you, manufacture it & give us all a dose." 

COVID-19 Vaccine

Frequently Asked Questions

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How does a vaccine work?

A vaccine works by mimicking a natural infection. A vaccine not only induces immune response to protect people from any future COVID-19 infection, but also helps quickly build herd immunity to put an end to the pandemic. Herd immunity occurs when a sufficient percentage of a population becomes immune to a disease, making the spread of disease from person to person unlikely. The good news is that SARS-CoV-2 virus has been fairly stable, which increases the viability of a vaccine.

How many types of vaccines are there?

There are broadly four types of vaccine — one, a vaccine based on the whole virus (this could be either inactivated, or an attenuated [weakened] virus vaccine); two, a non-replicating viral vector vaccine that uses a benign virus as vector that carries the antigen of SARS-CoV; three, nucleic-acid vaccines that have genetic material like DNA and RNA of antigens like spike protein given to a person, helping human cells decode genetic material and produce the vaccine; and four, protein subunit vaccine wherein the recombinant proteins of SARS-COV-2 along with an adjuvant (booster) is given as a vaccine.

What does it take to develop a vaccine of this kind?

Vaccine development is a long, complex process. Unlike drugs that are given to people with a diseased, vaccines are given to healthy people and also vulnerable sections such as children, pregnant women and the elderly. So rigorous tests are compulsory. History says that the fastest time it took to develop a vaccine is five years, but it usually takes double or sometimes triple that time.

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Aadar Poonawalla, chief executive officer of Serum Institute of India, responded to industrialist Anand Mahindra's "Big V" vaccine tweet.

"Haha! good one Anand Mahindra, my scientists are working on it!" Poonawalla said in response to Mahindra's tweet. Poonawalla also wished Bachchan on his recovery from COVID-19.

Poonawalla's Serum Institute of India has received regulatory approval to conduct human clinical trials of the experimental COVID-19 vaccine developed by Oxford University and AstraZeneca.

The wait for a vaccine doesn't seem to end anytime before this year's end. More and more manufacturers are sure on a timeline that extends into the Q1 of FY2021 when a number of vaccine manufacturers will be ready with their versions. Currently, China's Sinovac, Moderna from the US and Oxford-AstraZeneca are some of the foremost contenders to come up with a vaccine.

India's Bharat Biotech is also hoping to come out with its own version by this year's end.
First Published on Aug 4, 2020 11:05 am