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Glenmark inks deal with SaNOtize for COVID treatment spray in India, other Asian markets

Glenmark Pharmaceuticals and SaNOtize Research and Development Corp announced an exclusive long term strategic partnership to manufacture, market and distribute its breakthrough Nitric Oxide Nasal Spray (NONS)in Asian markets including India, Singapore, Malaysia, Hong Kong, Taiwan, Nepal, Brunei, Cambodia, Laos, Myanmar, Sri Lanka, Timor Leste and Vietnam, Glenmark said in a regulatory filing.

August 02, 2021 / 10:41 AM IST
 
 
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Drug firm Glenmark Pharmaceuticals on Monday said it has signed an agreement with Canadia's biotech firm SaNOtize Research and Development Corp to commercialise its Nitric Oxide Nasal Spray for COVID-19 treatment in India and other Asian markets

Glenmark Pharmaceuticals and SaNOtize Research and Development Corp announced an exclusive long term strategic partnership to manufacture, market and distribute its breakthrough Nitric Oxide Nasal Spray (NONS)in Asian markets including India, Singapore, Malaysia, Hong Kong, Taiwan, Nepal, Brunei, Cambodia, Laos, Myanmar, Sri Lanka, Timor Leste and Vietnam, Glenmark said in a regulatory filing.

Glenmark said in early July 2021, the company presented a proposal to the subject expert committee of CDSCO for emergency approval for import and marketing of the nasal spray.

"The committee has recommended a phase III clinical trial to be conducted in Indian patients in the weeks to follow. The phase III clinical trial for NONS is expected to be completed, followed by commercial launch under the brand name FabiSpray in India, by fourth quarter of the calendar year 2021," the company added.

“This partnership with SaNOtize closely aligns with Glenmark's focused approach against COVID-19 and will help reduce the burden of the pandemic in the region.” said Glenn Saldanha, Chairman and MD, Glenmark Pharmaceuticals.

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COVID-19 Vaccine

Frequently Asked Questions

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How does a vaccine work?

A vaccine works by mimicking a natural infection. A vaccine not only induces immune response to protect people from any future COVID-19 infection, but also helps quickly build herd immunity to put an end to the pandemic. Herd immunity occurs when a sufficient percentage of a population becomes immune to a disease, making the spread of disease from person to person unlikely. The good news is that SARS-CoV-2 virus has been fairly stable, which increases the viability of a vaccine.

How many types of vaccines are there?

There are broadly four types of vaccine — one, a vaccine based on the whole virus (this could be either inactivated, or an attenuated [weakened] virus vaccine); two, a non-replicating viral vector vaccine that uses a benign virus as vector that carries the antigen of SARS-CoV; three, nucleic-acid vaccines that have genetic material like DNA and RNA of antigens like spike protein given to a person, helping human cells decode genetic material and produce the vaccine; and four, protein subunit vaccine wherein the recombinant proteins of SARS-COV-2 along with an adjuvant (booster) is given as a vaccine.

What does it take to develop a vaccine of this kind?

Vaccine development is a long, complex process. Unlike drugs that are given to people with a diseased, vaccines are given to healthy people and also vulnerable sections such as children, pregnant women and the elderly. So rigorous tests are compulsory. History says that the fastest time it took to develop a vaccine is five years, but it usually takes double or sometimes triple that time.

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SaNOtize developed and patented a Nitric Oxide Releasing Solution platform technology (NORSTM) to treat and prevent microbial infections in 2017. Glenmark's partnership with SaNOtize will bring in much needed therapeutic relief to patients in India and Asia.
PTI
first published: Aug 2, 2021 10:42 am

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