Indian ADRs ended mixed on Thursday. ICICI Bank shed 0.06 percent and Tata Motors fell 0.60 percent.
The S&P 500 slipped 1.11 points, or 0.05 percent, to end at 2,434.50, with consumer staples leading seven sectors lower and health care outperforming. The Nasdaq rose 2.73 points, or 0.04 percent, to close at 6,236.69.
Japan's Nikkei stock index edged down slightly, but was on track to log a rise of 0.8 percent in a week in which it touched its highest levels since August 2015.
Indian ADRs ended mostly higher on Wednesday. Tata Motors rose 0.29 percent and Wipro was up 0.02 percent.
Japan's Nikkei and South Korea's KOSPI were flat, while Australian shares rose0.4 percent.
The Dow Jones Industrial Average fell 57.11 points, or 0.27 percent, to close at 21,410.03, the S&P 500 lost 1.42 points, or 0.06 percent, dropping to 2,435.61 and the Nasdaq Composite added 45.92 points, or 0.74 percent, rising to 6,233.95.
Indian ADRs ended lower on Tuesday. HDFC Bank fell 0.10 percent and Dr Reddy's Laboratories declined 0.25 percent.
The Nikkei 225 declined 0.26 percent and the Kospi fell 0.71 percent.
The Dow Jones Industrial Average was down 61.85 points, or 0.29 percent, to 21,467.14, the S&P 500 had lost 16.43 points, or 0.67 percent, to 2,437.03 and the Nasdaq Composite had dropped 50.98 points, or 0.82 percent, to 6,188.03.
Indian ADRs ended lower on Monday. ICICI Bank shed 0.11 percent and Wipro was down 0.08 percent.
The Nikkei 225 gained 0.86 percent and South Korea's benchmark Kospi index rose 0.45 percent in early trade.
The Dow Jones Industrial Average rose 144.71 points, or 0.68 percent, to end at 21,528.99, the S&P 500 gained 20.31 points, or 0.83 percent, to 2,453.46 and the Nasdaq Composite rose 87.26 points, or 1.42 percent, to 6,239.01.
Markets in greater China were in the green, with Hong Kong's Hang Seng Index gaining 0.56 percent. On the mainland, the Shanghai Composite added 0.22 percent and the Shenzhen Composite rose 0.273 percent.
Indian ADRs ended lower on Friday. Tata Motors shed 0.31 percent and Infosys was down 0.10 percent.
The Dow Jones Industrial Average rose 6.71 points, or 0.03 percent, to 21,366.61, the S&P 500 lost 1.65 points, or 0.07 percent, to 2,430.81 and the Nasdaq Composite dropped 9.45 points, or 0.15 percent, to 6,156.06.
Indian ADRs ended mostly higher on Thursday. Tata Motors was up 0.01 percent and HDFC Bank added 1.47 percent.
The Dow Jones Industrial Average fell 26.71 points, or 0.12 percent, to 21,347.85, the S&P 500 lost 6.87 points, or 0.28 percent, to 2,431.05 and the Nasdaq Composite dropped 34.08 points, or 0.55 percent, to 6,160.82
Indian ADRs ended mostly higher on Wednesday. Tata Motors was up 0.01 percent and ICICI Bank was up 0.13 percent.
The Nikkei 225 edged lower by 0.6 percent while the Kospi gave up earlier gains to decline 0.75 percent.
The Dow Jones Industrial Average rose 46.09 points, or 0.22 percent, to 21,374.56, the S&P 500 lost 2.43 points, or 0.10 percent, to 2,437.92 and the Nasdaq Composite dropped 25.48 points, or 0.41 percent, to 6,194.89.
The S&P 500 technology sector rose 0.9 percent, recovering from its biggest two-day decline in nearly a year that also weighed on the broader market. Big tech names, such as Microsoft and Facebook , pushed the S&P 500 higher.
MSCI's broadest index of Asia-Pacific shares outside Japan added 0.2 percent, while Japan's Nikkei put on 0.5 percent.
Indian ADRs ended lower on Tuesday. Tata Motors slipped 0.18 percent and Infosys fell 0.32 percent.
Indian ADRs ended mostly lower on Monday. ICICI Bank fell 0.20 percent, while Tata Motors was up 0.11 percent.
MSCI's broadest index of Asia-Pacific shares outside Japan rose 0.1 percent in early trade. Japan's Nikkei slipped 0.3 percent.