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Aveo Oncology, a cancer therapeutics company committed to discovering, developing and commercializing targeted therapies to impact patients' lives, has initiated phase 1 study examining the safety and preliminary efficacy of AV-203 along with exploratory ...
May 25, 2012 at 06:59 | Source: pharmabiz.com
Cancer Research UK's Drug Development Office has opened the first trial of a new drug combination in patients with advanced solid tumours and in a subset of patients who have non-small cell lung cancer. This trial will combine two compounds that ...
May 17, 2012 at 08:49 | Source: News-Medical.Net
Silence Therapeutics to Announce New Data from Phase I Study of Atu027 in Solid Tumours At 2012 ASCO Annual Meeting Silence Therapeutics plc (AIM: SLN) ("Silence" or the "Company"), a leading global RNA interference (RNAi) therapeutics company, today ...
May 17, 2012 at 06:12 | Source: PR Newswire
The most common BRAF mutations are Val600Lys and Val600Glu. A total of 184 patients with incurable solid tumours were enrolled into the study (156 of these patients with metastatic melanoma) and given escalating doses of dabrafenib. The initial phase of ...
May 21, 2012 at 23:03 | Source: CBS42.com
Researchers from the Cancer Research UK's Drug Development Office have developed a new drug combination - vandetanib and selumetinib - for patients who have advanced solid tumours. They claim that the two-drug combination will starve the tumours by ...
May 17, 2012 at 06:12 | Source: ibtimes.co.uk
"Until now, immunotherapy has not been very successful in treating cancer because tumours are very resistant to immune ... "As a cancerous tumour grows, it forms a solid ball which is difficult for immune cells to get into and even if they ...
May 28, 2012 at 10:16 | Source: medicalxpress.com
Bionomics chief executive Deborah Rathjen said preclinical trials had shown that the compound helped improve survival rates in animals with solid tumours. It shuts down blood vessels in the tumour and starves it, without affecting normal blood vessels ...
May 24, 2012 at 07:22 | Source: Adelaidenow
Tumours are usually very resistant to immune cells ... "As a cancerous tumour grows, it forms a solid ball which is difficult for immune cells to get into and even if they can penetrate the tumour, the environment inside it either kills the ...
May 27, 2012 at 12:55 | Source: Eureka! Science News
“The design of this clinical trial is based on robust preclinical data demonstrating synergy between BNC105 and platinum-based therapies in improving survival rates of animals with solid tumours”. “There is extremely promising data around this ...
May 24, 2012 at 11:40 | Source: Phramalive.com
Administered Orally QD to Patients with Advanced Solid E7050 Tumours Abstract No: 3030 Poster Discussion A Phase I Dose-Finding Study of Golvatinib (E7050), a c-Met and EPH Receptor Targeted Multi-Kinase Inhibitor Administered Orally BID to Patients with ...
May 17, 2012 at 23:01 | Source: PressePortal.de